# Blocks Search Results

- Go To Hits

###

    Introduction

    BLKPROB Version  4/ 8/99.1
    Database=../data-blplus/blocks.dat
            ___________               ___________               ___________
           |\ __________\            |___________|            /__________ /|
           | |           |           |           |           |           | |
           | | **********|           |***********|           |********** | |
           | | * BLOCKS  |           |EMAIL & WWW|           |SEARCHER * | |
           | | **********|           |***********|           |********** | |
            \|___________|___________|___________|___________|___________|/
                         |\ __________\         /__________ /|
                         | |  blocks@  |       | http://   | |
                         | |   blocks. |       |  blocks.  | |
                         | |   fhcrc.  |       |  fhcrc.   | |
                         | |   org     |       |  org      | |
                          \|___________|       |___________|/

    Here are your search results. The database searched was Blocks+ (19 Mar 99)
    which includes: BLOCKS 11.0 consisting of 4034 blocks representing 994 groups
    documented in PROSITE 15, plus 2277 blocks from 352 groups documented in
    PRINTS 22.0 but not represented in BLOCKS, plus 1083 blocks from 254 groups
    documented in PFAM 3.4 but not represented in BLOCKS or PRINTS, plus
    1035 blocks from 268 groups documented in PRODOM 36 but not represented in
    BLOCKS, PRINTS or PFAM, plus 480 blocks from 127 groups documented in DOMO 2.0
    but not represented in BLOCKS, PRINTS, PFAM or PRODOM for a total of 8909
    blocks from 1995 groups.  Get more information at http://blocks.fhcrc.org.
    If you found the Blocks Searcher useful, please cite:
       S Henikoff & JG Henikoff, "Protein family classification
       based on searching a database of blocks", Genomics 19:97-107 (1994).
    ==============================================================================
    Each numbered result consists of one or more blocks from a Prosite group found
    in the query sequence. One set of the highest-scoring blocks that are in the
    correct order and separated by distances comparable to the Blocks database is
    selected for analysis. If this set includes multiple blocks the probability
    that the lower scoring blocks support the highest scoring block is reported.
    Maps of the database blocks and query sequence are shown:
    AAA represents the first block roughly in proportion to its width.
      : represents the minimum distance between blocks in the database.
      . represents the maximum distance between blocks in the database.
    < > indicate the sequence has been truncated to fit the page.
    The query map is aligned on the highest scoring block. Multiple block hits
    that are consistent with the highest scoring block are separated by colons.
    Block hits that are not consistent are mapped below. The alignment of the
    query sequence with the sequence closest to it in the BLOCKS database is
    shown. The distance between detected blocks is listed as (min, max): for the
    database entry followed by the distance in the query. Upper case in the query
    indicates at least one occurrence of the residue in that column of the block.

    For interpretation of block hits, you might find it worthwhile to obtain the
    full set of blocks and documentation for a group. To do this, send a blank
    message to blocks@blocks.fhcrc.org with the subject heading: GET BL????? e.g.,
    'Subject: GET BL00044' (0s are zeros) for full information on this group.
    =============================================================================
    Note: For searches using DNA queries, "Location" refers to the position
    in the query in base pairs from 5' to 3' on the + strand, whereas the map and
    alignment show the translated position in amino acid residues as before.
    =============================================================================

[Return to top]

###

    Hits
    Query=gi|2332305|gb|AA560840|AA560840  vk94e04.r1 Knowles Solter mouse blastocyst B1 M
    Size=642 Base Pairs
    Blocks Searched=8909
    Alignments Done=12815646
    Cutoff Expected Value=  2
    ==============================================================================
                                                               Anchor   Combined
    Family                                     Strand Blocks   E-value  E-value
    BL50040 Elongation factor 1 gamma chain pro   1   3 of 7   7.9e-32  5.5e-65
    DM01181 7 kw 103-1A LACTOYLGLUTATHIONE GLUT   1   1 of 3   4.8e-05  4.6e-05
    PF00043 Glutathione S-transferases.           1   1 of 1    0.0028   0.0026
    BL00702 Granulocyte-macrophage colony-stimu   1   1 of 4      0.24     0.22
    BL00421 Transmembrane 4 family proteins.      1   1 of 5      0.47     0.42
    PR00614 NI-FE HYDROGENASE SMALL SUBUNIT SIG   1   1 of 11     0.77     0.71
    BL00415 Synapsins proteins.                   1   1 of 19      2.1        2

    ==============================================================================
    >BL50040 3/7 blocks: Elongation factor 1 gamma chain profile.
    Block    Frame    Location (bp)   Position p-value
    BL50040A    3          6-39             1.7e-14
    BL50040B    2        152-227            7.2e-30
    BL50040C    1        397-523            1.2e-38
    Other reported alignments:

                             |---  186 amino acids---|
         BL50040 AA:::..BBB::::::...CCCCCC::::::::::...DDDDDDDEEEEEEEFFFFF.G
              gi  AA:::::BBB::::::::CCCCCC

    BL50040A    <->A   (2,3):1        BL50040B   A<->B   (25,37):37
    EF1G_HUMAN 4       GTLYTYPENWRA   EF1G_HUMAN 53      FPAGKVPAFEGDDGFCVFESNAIAYY
                       ||||||||||||                      ||||||||||||||||||||||||||
    gi         2       GTLYTYPENWRA   gi         51      FPAGKVPAFEGDDGFCVFESNAIAYY

    BL50040C   B<->C   (47,66):56
    EF1G_RABIT 135     VKRILGLLDAHLKTRTFLVGERVTLADITVVCTLLWLYKQVLE
                       ||||||||| |||||||||||||||||||||||||||||||||
    gi         133     VKRILGLLDtHLKTRTFLVGERVTLADITVVCTLLWLYKQVLE

    ------------------------------------------------------------------------------
    >DM01181 1/3 blocks: 7 kw 103-1A LACTOYLGLUTATHIONE GLUTATHIONE LYASE.
    Block    Frame    Location (bp)   Position p-value
    DM01181C    1        367-478            7.5e-12
    Other reported alignments:

                             |---   63 amino acids---|
         DM01181 AAAAAAAAAAAAAAAAAAAAAA::::::...BBBBBBBBB::::.CCCCCCCCCCCCCCC
              gi <::::::::::::::::::::::::::::::::::::::::::::CCCCCCCCCCCCCCC

    DM01181C    <->C   (112,128):122
    GTX1_TOBAC 115     GEEQEKDKEEVCEMLKVLDNELKDKKFFVGDKFGFADI
                           |  ||||   |  ||  ||   | ||     |||
    gi         123     kqAtEnAKEEVkrILgLLDthLKtRTFlVGErVtLADI

    ------------------------------------------------------------------------------
    >PF00043 1/1 blocks: Glutathione S-transferases.
    Block    Frame    Location (bp)   Position p-value
    PF00043     2        164-251            4.4e-10
    Up to 1 repeats expected:
    PF00043     2        167-254            8.5e-07
    Other reported alignments:

    PF00043     <->
    EF1G_HUMAN 57      KVPAFEGDDGFCVFESNAIAYYVSNEELRG
                       ||||||||||||||||||||||||||||||
    gi         55      KVPAFEGDDGFCVFESNAIAYYVSNEELRG
               56      VPAFEGDDGFCVFESNAIAYYVSNEELRGS

    ------------------------------------------------------------------------------
    >BL00702 1/4 blocks: Granulocyte-macrophage colony-stimulating factor proteins.
    Block    Frame    Location (bp)   Position p-value
    BL00702B    1        430-532            3.7e-08
    Other reported alignments:

                             |---   60 amino acids---|
         BL00702 AAAAAAAAAAAAAAAAA:::.BBBBBBBBBBBBBBBCCCCCCCCCCCCDDDDDDDDDDDD
              gi <::::::::::::::::::::BBBBBBBBBBBBBBB

    BL00702B    <->B   (32,52):143
    CSF2_PIG   53      MNETVDVVCEMFDPQEPTCVQTRLNLYKQGLRGSL
                              | |       | | | | |||| |  |
    gi         144     LktrTflVgErvtLadiTvVcTlLwLYKQvLepSF

    ------------------------------------------------------------------------------
    >BL00421 1/5 blocks: Transmembrane 4 family proteins.
    Block    Frame    Location (bp)   Position p-value
    BL00421C    2        479-512            7.3e-08
    Other reported alignments:

                             |---  107 amino acids---|
         BL00421 AAAA:::::::..BBBBBBBBB::::::::::..CCC:....D::.........EEEEEEE
              gi <:::::::::::::::::::::::::::::::::CCC

    BL00421C    <->C   (132,154):159
    C151_HUMAN 149     LQQEFHCCGSNN
                       ||    |||| |
    gi         160     LQlSVpCCGSiN

    ------------------------------------------------------------------------------
    >PR00614 1/11 blocks: NI-FE HYDROGENASE SMALL SUBUNIT SIGNATURE
    Block    Frame    Location (bp)   Position p-value
    PR00614I    1          1-79             1.2e-07
    Other reported alignments:

                             |---  112 amino acids---|
         PR00614 AAAAABBBBBB::::.CCCCC:.DDDEEEEEE:.FFFFFGGGGHHHH:IIIIIIJJJKKK
              gi                                                 IIIIII

    PR00614I    <->I   (204,283):0
    MBHS_ALCHY 254     RKGYCLYKVGCKGPTTYNACSTTRWNG
                       | | |       || |   ||  |  |
    gi         1       RlGpCthtLkigGPsTsvrCSvQRgsG

    ------------------------------------------------------------------------------
    >BL00415 1/19 blocks: Synapsins proteins.
    Block    Frame    Location (bp)   Position p-value
    BL00415Q    1         40-145            3.3e-07       biased
    Other reported alignments:

                             |---  294 amino acids---|
         BL00415 AAABBBCCCDDDEEEFFFGGHHHHIIJJKKKKLLMMMNNNN::OOOPPPQQQRRRSSS
              gi                                                 :QQQ

    BL00415Q    <->Q   (594,596):13
    SYN1_RAT   595     PAGPIRQASQAGPGPRTGPPTTQQPRPSGPGPAGRP
                       |    |   | | |||    |     |  | |   |
    gi         14      PstsvRcsvQrGsGPRalrtTplplwPnqPhP*isP

    ------------------------------------------------------------------------------

    7 possible hits reported

[Return to top] [Blocks Home]