
BLKSORT Version  8/21/02.1
Database=sample.blocks
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==============================================================================
      Attention Blocks E-mail users: See new searching options at
	      http://blocks.fhcrc.org/help/email.html
==============================================================================
Here are your search results. The database searched was Blocks+ (10 June 00)
which includes: BLOCKS 12.0 consisting of 4071 blocks representing 998 groups
documented in InterPro 1.0/PROSITE, plus 3141 blocks from 498 groups documented 
in PRINTS 26.0 but not represented in BLOCKS, plus 2382 blocks from 569 groups 
documented in PFAM 5.3 but not represented in BLOCKS or PRINTS, plus
962 blocks from 250 groups documented in PRODOM 99.1 but not represented in
BLOCKS, PRINTS or PFAM, plus 282 blocks from 76 groups documented in DOMO 2.0
but not represented in BLOCKS, PRINTS, PFAM or PRODOM for a total of 10,838
blocks from 2391 groups.  Get more information at http://blocks.fhcrc.org.
If you found the Blocks Searcher useful, please cite:
   S Henikoff & JG Henikoff, "Protein family classification
   based on searching a database of blocks", Genomics 19:97-107 (1994).
Please report problems to:  webmaster@blocks.fhcrc.org
==============================================================================
Each numbered result consists of one or more blocks from a Prosite group found
in the query sequence. One set of the highest-scoring blocks that are in the 
correct order and separated by distances comparable to the Blocks database is 
selected for analysis. If this set includes multiple blocks the probability 
that the lower scoring blocks support the highest scoring block is reported. 
Maps of the database blocks and query sequence are shown:
AAA represents the first block roughly in proportion to its width.
  : represents the minimum distance between blocks in the database.
  . represents the maximum distance between blocks in the database.
< > indicate the sequence has been truncated to fit the page.
The query map is aligned on the highest scoring block. Multiple block hits 
that are consistent with the highest scoring block are separated by colons.
Block hits that are not consistent are mapped below. The alignment of the
query sequence with the sequence closest to it in the BLOCKS database is
shown. The distance between detected blocks is listed as (min, max): for the
database entry followed by the distance in the query. Upper case in the query
indicates at least one occurrence of the residue in that column of the block.

The following nomogram is provided to aid interpretation of scores and 
probability estimates. It summarizes results from 7,082 searches using 
shuffled protein queries. "Shuffled percentiles" are calculated from scores
obtained for the top-scoring block in each search:

   1400 *-----------|-----------|-----------|-----------|100.00  
        |\                                              |        
        | \                                             |        
   1350 -  \                                            - 99.99  
        |   \                                           |        
        |    \               < 1/7000 searches          |        
   1300 -     \                                         - 99.96 S
 A      *      \                                        |       H
 N      | \     \                                       |       U
 C 1250 -  \     \                                      - 99.82 F
 H      |   \     \                                     |       F
 O      |    \     \                                    |       L
 R 1200 -     \     * \ \ \ \                           - 99.60 E
        |      \              \ *  \                    |       D
 B      |        \   < 1/1000         \                 |
 L 1150 *           *   searches        \               - 98.80 P
 O      | \           \ \                 \             |       E
 C      |    \            \ \               *           |       R
 K 1100 -       \             \ * \ \ \ \ \   \         - 92.28 C
        |           *   < 1/100 searches    *   \       |       E
 S      |              \                     \    \     |       N
 C 1050 -                 \ \ \ * \            \    \   - 53.16 T
 O      |                           \ \ \         \  \  |       I
 R      |                                 \          \\ |       L
 E 1000 |-----------|-----------|-----------|-----------|  0.00 E
        0          -1          -2          -3          -4 
                             LOG(P)

For example, a first hit with anchor block score of 1150 (98.80th percentile)
and estimated P-value of .01 (log(P) = -2) is expected to occur by chance
less than once in 1000 searches but more than once in 7000 searches
using protein queries of typical length and composition. It is not appropriate
to apply this nomogram to hits other than the first hit reported.

For interpretation of block hits, you might find it worthwhile to obtain the
full set of blocks and documentation for a group. To do this, send a blank
message to blocks@blocks.fhcrc.org with the subject heading: GET BL????? e.g.,  
'Subject: GET BL00044' (0s are zeros) for full information on this group.
=============================================================================
Note: For searches using DNA queries, "Location" refers to the position
in the query in base pairs from 5' to 3' on the + strand, whereas the map and 
alignment show the translated position in amino acid residues as before.
============================================================================= 

Query=HAIR_DROME  HAIRY PROTEIN 
, 
 Size=337 Amino Acids
Blocks Searched=9

1.------------------------------------------------------------------------
Block     Rank Frame Score Strength   Location (aa) Description
IPB001092A     2   0   1104   960          40-     51 Basic helix-loop-helix d
IPB001092A     5   0    941   960         129-    140 Basic helix-loop-helix d
IPB001092A    22   0    893   960         127-    138 Basic helix-loop-helix d
IPB001092A    23   0    891   960         100-    111 Basic helix-loop-helix d
IPB001092A    36   0    880   960          41-     52 Basic helix-loop-helix d
IPB001092A    55   0    868   960          35-     46 Basic helix-loop-helix d
IPB001092A    76   0    863   960         128-    139 Basic helix-loop-helix d
IPB001092A    82   0    861   960         125-    136 Basic helix-loop-helix d
IPB001092A    86   0    860   960         133-    144 Basic helix-loop-helix d
IPB001092A    99   0    857   960         130-    141 Basic helix-loop-helix d
IPB001092A   134   0    848   960          43-     54 Basic helix-loop-helix d
IPB001092A   151   0    845   960         148-    159 Basic helix-loop-helix d
IPB001092A   165   0    839   960         149-    160 Basic helix-loop-helix d
IPB001092A   171   0    838   960          39-     50 Basic helix-loop-helix d
IPB001092A   178   0    836   960         310-    321 Basic helix-loop-helix d
IPB001092A   179   0    836   960         316-    327 Basic helix-loop-helix d
IPB001092A   196   0    833   960          65-     76 Basic helix-loop-helix d
IPB001092A   212   0    831   960          30-     41 Basic helix-loop-helix d
IPB001092A   213   0    831   960          96-    107 Basic helix-loop-helix d
IPB001092A   219   0    830   960          91-    102 Basic helix-loop-helix d
IPB001092A   236   0    826   960          47-     58 Basic helix-loop-helix d
IPB001092A   252   0    824   960          44-     55 Basic helix-loop-helix d
IPB001092A   253   0    824   960         261-    272 Basic helix-loop-helix d
IPB001092A   257   0    823   960          28-     39 Basic helix-loop-helix d
IPB001092A   258   0    823   960         152-    163 Basic helix-loop-helix d
IPB001092A   275   0    820   960         151-    162 Basic helix-loop-helix d
IPB001092A   281   0    819   960         259-    270 Basic helix-loop-helix d
IPB001092A   288   0    818   960         117-    128 Basic helix-loop-helix d
IPB001092A   301   0    816   960         231-    242 Basic helix-loop-helix d
IPB001092A   303   0    815   960          88-     99 Basic helix-loop-helix d
IPB001092A   304   0    815   960         233-    244 Basic helix-loop-helix d
IPB001092A   322   0    812   960          42-     53 Basic helix-loop-helix d
IPB001092A   337   0    810   960          31-     42 Basic helix-loop-helix d
IPB001092A   338   0    810   960         172-    183 Basic helix-loop-helix d
IPB001092A   344   0    809   960         136-    147 Basic helix-loop-helix d
IPB001092A   345   0    809   960         236-    247 Basic helix-loop-helix d
IPB001092A   373   0    805   960          79-     90 Basic helix-loop-helix d
IPB001092A   388   0    803   960          25-     36 Basic helix-loop-helix d
IPB001092A   389   0    803   960         234-    245 Basic helix-loop-helix d
IPB001092B     1   0   1107   991          71-     85 Basic helix-loop-helix d
IPB001092B    19   0    900   991          52-     66 Basic helix-loop-helix d
IPB001092B    41   0    876   991          33-     47 Basic helix-loop-helix d
IPB001092B    61   0    866   991           7-     21 Basic helix-loop-helix d
IPB001092B    66   0    864   991          65-     79 Basic helix-loop-helix d
IPB001092B    67   0    864   991         170-    184 Basic helix-loop-helix d
IPB001092B    77   0    863   991          89-    103 Basic helix-loop-helix d
IPB001092B    87   0    860   991          68-     82 Basic helix-loop-helix d
IPB001092B   110   0    855   991         108-    122 Basic helix-loop-helix d
IPB001092B   111   0    855   991         126-    140 Basic helix-loop-helix d
IPB001092B   124   0    851   991         295-    309 Basic helix-loop-helix d
IPB001092B   135   0    848   991         206-    220 Basic helix-loop-helix d
IPB001092B   161   0    841   991         316-    330 Basic helix-loop-helix d
IPB001092B   166   0    839   991         181-    195 Basic helix-loop-helix d
IPB001092B   167   0    839   991         189-    203 Basic helix-loop-helix d
IPB001092B   173   0    837   991          74-     88 Basic helix-loop-helix d
IPB001092B   180   0    836   991         308-    322 Basic helix-loop-helix d
IPB001092B   203   0    832   991         252-    266 Basic helix-loop-helix d
IPB001092B   204   0    832   991         317-    331 Basic helix-loop-helix d
IPB001092B   214   0    831   991          44-     58 Basic helix-loop-helix d
IPB001092B   222   0    829   991         234-    248 Basic helix-loop-helix d
IPB001092B   223   0    828   991          63-     77 Basic helix-loop-helix d
IPB001092B   224   0    828   991         129-    143 Basic helix-loop-helix d
IPB001092B   227   0    827   991          80-     94 Basic helix-loop-helix d
IPB001092B   237   0    826   991          98-    112 Basic helix-loop-helix d
IPB001092B   246   0    825   991         227-    241 Basic helix-loop-helix d
IPB001092B   254   0    824   991         209-    223 Basic helix-loop-helix d
IPB001092B   269   0    821   991           5-     19 Basic helix-loop-helix d
IPB001092B   270   0    821   991         298-    312 Basic helix-loop-helix d
IPB001092B   289   0    818   991          84-     98 Basic helix-loop-helix d
IPB001092B   290   0    818   991         231-    245 Basic helix-loop-helix d
IPB001092B   296   0    817   991         229-    243 Basic helix-loop-helix d
IPB001092B   311   0    814   991          13-     27 Basic helix-loop-helix d
IPB001092B   323   0    812   991          56-     70 Basic helix-loop-helix d
IPB001092B   324   0    812   991         157-    171 Basic helix-loop-helix d
IPB001092B   339   0    810   991         105-    119 Basic helix-loop-helix d
IPB001092B   340   0    810   991         215-    229 Basic helix-loop-helix d
IPB001092B   346   0    809   991          21-     35 Basic helix-loop-helix d
IPB001092B   351   0    808   991          32-     46 Basic helix-loop-helix d
IPB001092B   352   0    808   991          97-    111 Basic helix-loop-helix d
IPB001092B   363   0    806   991          51-     65 Basic helix-loop-helix d
IPB001092B   364   0    806   991         236-    250 Basic helix-loop-helix d
IPB001092B   374   0    805   991         233-    247 Basic helix-loop-helix d
IPB001092B   381   0    804   991          81-     95 Basic helix-loop-helix d
IPB001092B   382   0    804   991         176-    190 Basic helix-loop-helix d
IPB001092B   383   0    804   991         253-    267 Basic helix-loop-helix d
IPB001092B   395   0    802   991           0-     14 Basic helix-loop-helix d
IPB001092B   396   0    802   991         313-    327 Basic helix-loop-helix d

1107=94.06th percentile of anchor block scores for shuffled queries
P< 0.047 for IPB001092A in support of IPB001092B
                         |--- 2957 amino acids---|
         IPB001092 A............................................................B
        HAIR_DROME                                                             AB
        HAIR_DROME                                                             
        HAIR_DROME                                                             

IPB001092A          <->9   (-2,3229):39
HAIR_DROVI|P29303  46      EKRRRARINNCL
                           ||||||||||||
HAIR_DROME         40      EKRRRARINNCL

IPB001092B         9<->9   (-2,7069):19   
HAIR_DROVI|P29303  77      KLEKADILEKTVKHL
                           |||||||||||||||
HAIR_DROME         71      KLEKADILEKTVKHL

1 possible hits reported
