>P1;M63632
   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
MNGTEGD---------------------------NFYVP-------F---
---------------------SN-KTG-----------------LA--RS
PYEYPQYY-LAEPWKYSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTP
LNYILLNLAMANLFMVLF-GFTVTM-YTSMN-GYFVFGPTMCSIEGFFAT
LGGEVALWSLVVLAIERYIVICKPMGN-FRFGNTHAIMGVAFTWIMALAC
-AAPPL-VGWSR-----YIPEGMQ---CSCGPDYYTLNPNFNNESYVVYM
FVVHFLVPFVIIFFCYGRLLCTVKEAAAAQ--------------------
--------------------------------------------------
-------------------------------Q------------------
-----------------------------------------------ES-
ASTQKAEKEVTRMVVLMVIGFLVCWVPYASVAFYIFTHQGSD--FGAT-F
MTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLC----C-GKNPLGDDE
-SG-AS-TSKTEVS-------------S----------------------
--------------------------------------------------
------------------VSTSPVSPA
*
>P1;U22180
   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
MNGTEGP---------------------------NFYVP-------F---
---------------------SN-ITG-----------------VV--RS
PFEQPQYY-LAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTP
LNYILLNLAVADLFMVFG-GFTTTL-YTSLH-GYFVFGPTGCNLEGFFAT
LGGEIGLWSLVVLAIERYVVVCKPMSN-FRFGENHAIMGVAFTWVMALAC
-AAPPL-VGWSR-----YIPEGMQ---CSCGIDYYTLKPEVNNESFVIYM
FVVHFTIPMIVIFFCYGQLVFTVKEAAAQQ--------------------
--------------------------------------------------
-------------------------------Q------------------
-----------------------------------------------ES-
ATTQKAEKEVTRMVIIMVIFFLICWLPYASVAMYIFTHQGSN--FGPI-F
MTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLC----C-GKNPLGDDE
-AS-AT-ASKTE--------------------------------------
--------------------------------------------------
--------------------TSQVAPA
*
>P1;M92038
   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
MNGTEGI---------------------------NFYVP-------M---
---------------------SN-KTG-----------------VV--RS
PFEYPQYY-LAEPWKYRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQP
LNYILVNLAVADLFMACF-GFTVTF-YTAWN-GYFVFGPVGCAVEGFFAT
LGGQVALWSLVVLAIERYIVVCKPMGN-FRFSATHAMMGIAFTWVMAFSC
-AAPPL-FGWSR-----YMPEGMQ---CSCGPDYYTHNPDYHNESYVLYM
FVIHFIIPVVVIFFSYGRLICKVREAAAQQ--------------------
--------------------------------------------------
-------------------------------Q------------------
-----------------------------------------------ES-
ATTQKAEKEVTRMVILMVLGFMLAWTPYAVVAFWIFTNKGAD--FTAT-L
MAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTIC----C-GKNPFGDED
VSSTVS-QSKTEVS-------------S----------------------
--------------------------------------------------
------------------VSSSQVSPA
*
>P1;A45229
 opsin, green-sensitive (clone GFgr-1) - goldfish
MNGTEGK---------------------------NFYVP-------M---
---------------------SN-RTG-----------------LV--RS
PFEYPQYY-LAEPWQFKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQP
LNFILVNLAVAGTIMVCF-GFTVTF-YTAIN-GYFVLGPTGCAVEGFMAT
LGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSSHAFAGIAFTWVMALAC
-AAPPL-FGWSR-----YIPEGMQ---CSCGPDYYTLNPDYNNESYVIYM
FVCHFILPVAVIFFTYGRLVCTVKAAAAQQ--------------------
--------------------------------------------------
-------------------------------Q------------------
-----------------------------------------------DS-
ASTQKAEREVTKMVILMVFGFLIAWTPYATVAAWIFFNKGAD--FSAK-F
MAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIF----C-GKNPLGDDE
-SSTVS-TSKTE--------------------------------------
--------------------------------------------------
--------------------VSSVSPA
*
>P1;B45229
 opsin, green-sensitive (clone GFgr-2) - goldfish
MNGTEGN---------------------------NFYVP-------L---
---------------------SN-RTG-----------------LV--RS
PFEYPQYY-LAEPWQFKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQP
LNFILVNLAVAGAIMVCF-GFTVTF-YTAIN-GYFALGPTGCAVEGFMAT
LGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSTHASAGIAFTWVMAMAC
-AAPPL-VGWSR-----YIPEGIQ---CSCGPDYYTLNPEYNNESYVLYM
FICHFILPVTIIFFTYGRLVCTVKAAAAQQ--------------------
--------------------------------------------------
-------------------------------Q------------------
-----------------------------------------------DS-
ASTQKAEREVTKMVILMVLGFLVAWTPYATVAAWIFFNKGAA--FSAQ-F
MAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLF----C-GKNPLGDEE
-SSTVS-TSKTE--------------------------------------
--------------------------------------------------
--------------------VSSVSPA
*
>P1;L11864
   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
MKQVPEFH-E------------------------DFYIP-------I---
-----------------P--LDI-NNL-----------------SA--YS
PFLVPQDH-LGNQGIFMAMSVFMFFIFIGGASINILTILCTIQFKKLRSH
LNYILVNLSIANLFVAIF-GSPLSF-YSFFN-RYFIFGATACKIEGFLAT
LGGMVGLWSLAVVAFERWLVICKPLGN-FTFKTPHAIAGCILPWISALAA
-SLPPL-FGWSR-----YIPEGLQ---CSCGPDWYTTNNKYNNESYVMFL
FCFCFAVPFGTIVFCYGQLLITLKLAAKAQ--------------------
--------------------------------------------------
-------------------------------A------------------
-----------------------------------------------DS-
ASTQKAEREVTKMVVVMVLGFLVCWAPYASFSLWIVSHRGEE--FDLR-M
ATIPSCLSKASTVYNPVIYVLMNKQFRSCMMKMV-----C-GKNIE-EDE
-AS-TS-SQVTQVS------------------------------------
--------------------------------------------------
---------------------SVAPEK
*
>P1;M13299
   1 human BCP <>[Science232(4747),193-202'86]
MRKMSEE---------------------------EFYL--------F---
---------------------KN-IS-------------------S--VG
PWDGPQYH-IAPVWAFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQP
LNYILVNVSFGGFLLCIF-SVFPVF-VASCN-GYFVFGRHVCALEGFLGT
VAGLVTGWSLAFLAFERYIVICKPFGN-FRFSSKHALTVVLATWTIGIGV
-SIPPF-FGWSR-----FIPEGLQ---CSCGPDWYTVGTKYRSESYTWFL
FIFCFIVPLSLICFSYTQLLRALKAVAAQQ--------------------
--------------------------------------------------
-------------------------------Q------------------
-----------------------------------------------ES-
ATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHG--LDLR-L
VTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMV-----C-GKAMTDESD
T---CS-SQKTEVS-------------T----------------------
--------------------------------------------------
------------------VSSTQVGPN
*
>P1;K03494
   1 human GCP <>[Science232(4747),193-202'86]
MAQQWSLQ-RLAGRH---PQD--S--YEDSTQSSIFTYT-------N---
---------------------SN---------------------ST--RG
PFEGPNYH-IAPRWVYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHP
LNWILVNLAVADLAETVI-ASTISV-VNQVY-GYFVLGHPMCVLEGYTVS
LCGITGLWSLAIISWERWMVVCKPFGN-VRFDAKLAIVGIAFSWIWAAVW
-TAPPI-FGWSR-----YWPHGLK---TSCGPDVFSGSSYPGVQSYMIVL
MVTCCITPLSIIVLCYLQVWLAIRAVAKQQ--------------------
--------------------------------------------------
-------------------------------K------------------
-----------------------------------------------ES-
ESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYP--FHPL-M
AALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFG------KKVDDGS-E
LSSASK----TEVS-------------S----------------------
--------------------------------------------------
--------------------VSSVSPA
*
>P1;Z68193
   1 human Red Opsin <>[]
MAQQWSLQ-RLAGRH---PQD--S--YEDSTQSSIFTYT-------N---
---------------------SN---------------------ST--RG
PFEGPNYH-IAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHP
LNWILVNLAVADLAETVI-ASTISI-VNQVS-GYFVLGHPMCVLEGYTVS
LCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGIAFSWIWSAVW
-TAPPI-FGWSR-----YWPHGLK---TSCGPDVFSGSSYPGVQSYMIVL
MVTCCIIPLAIIMLCYLQVWLAIRAVAKQQ--------------------
--------------------------------------------------
-------------------------------K------------------
-----------------------------------------------ES-
ESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYA--FHPL-M
AALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFG------KKVDDGS-E
LSSASK----TEVS-------------S----------------------
--------------------------------------------------
--------------------VSSVSPA
*
>P1;M92036
   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
MTEAWNVA-VFAARR---SR---D--DDDTTRGSVFTYT-------N---
---------------------TN---------------------NT--RG
PFEGPNYH-IAPRWVYNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHP
LNWILVNLAFVDLVETLV-ASTISV-FNQIF-GYFILGHPLCVIEGYVVS
SCGITGLWSLAIISWERWFVVCKPFGN-IKFDSKLAIIGIVFSWVWAWGW
-SAPPI-FGWSR-----YWPHGLK---TSCGPDVFSGSVELGCQSFMLTL
MITCCFLPLFIIIVCYLQVWMAIRAVAAQQ--------------------
--------------------------------------------------
-------------------------------K------------------
-----------------------------------------------ES-
ESTQKAEREVSRMVVVMIVAFCICWGPYASFVSFAAANPGYA--FHPL-A
AALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLFG------KKVDDGS-E
ASTTSR----TEVS-------------S----------------------
--------------------------------------------------
------------------VSNSSVAPA
*
>P1;M62903
   1 chicken visual pigment <>[BBRC173,1212-1217'90]
MAAWEAAF-AA--RR----RH--E--EEDTTRDSVFTYT-------N---
---------------------SN---------------------NT--RG
PFEGPNYH-IAPRWVYNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHP
LNWILVNLAVADLGETVI-ASTISV-INQIS-GYFILGHPMCVVEGYTVS
ACGITALWSLAIISWERWFVVCKPFGN-IKFDGKLAVAGILFSWLWSCAW
-TAPPI-FGWSR-----YWPHGLK---TSCGPDVFSGSSDPGVQSYMVVL
MVTCCFFPLAIIILCYLQVWLAIRAVAAQQ--------------------
--------------------------------------------------
-------------------------------K------------------
-----------------------------------------------ES-
ESTQKAEKEVSRMVVVMIVAYCFCWGPYTFFACFAAANPGYA--FHPL-A
AALPAYFAKSATIYNPIIYVFMNRQFRNCILQLFG------KKVDDGS-E
V-STSR----TEVS-------------S----------------------
--------------------------------------------------
------------------VSNSSVSPA
*
>P1;S75720
   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
MSSNSSQA--------------------------------------P---
---------------------PN---------------------GT--PG
PFDGPQWPYQAPQSTYVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSP
LNYILVNLAVADLLVTLC-GSSVSL-SNNIN-GFFVFGRRMCELEGFMVS
LTGIVGLWSLAILALERYVVVCKPLGD-FQFQRRHAVSGCAFTWGWALLW
-SAPPL-LGWSS-----YVPEGLR---TSCGPNWYTGG--SNNNSYILSL
FVTCFVLPLSLILFSYTNLLLTLRAAAAQQ--------------------
--------------------------------------------------
-------------------------------K------------------
-----------------------------------------------EA-
DTTQRAEREVTRMVIVMVMAFLLCWLPYSTFALVVATHKGII--IQPV-L
ASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLC----C-GYQPQRT-G
KASPGTPGPHADVT---------AAGLR----------------------
--------------------------------------------------
------------------NKVMPAHPV
*
>P1;M17718
   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
MESGNVSS-SL-FGN-VSTA-----------LRPEA-RL-------S---
------------------A--E--TR---------LLGWNVPPEELRHIP
EH-WLTYP-EPPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTP
SNILVINLAFCDFMMM-V-KTPIFI-YNSFH-QGYALGHLGCQIFGIIGS
YTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMIIFIYMYATPW
-VVACYTETWGR-----FVPEGYL---TSCTFDYLTDN--FDTRLFVACI
FFFSFVCPTTMITYYYSQIVGHVFSHEKAL--------------------
--------------------------------------------------
-------------------------------RDQ------A---------
------------K----------------------KMNVESL---RSNVD
KNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAFGDKTL--LTPG-A
TMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLA--LNEK-AP-ES
-SAVAS-TSTT----------------Q----------------------
--------------------------------------------------
-------------------EPQQTTAA
*
>P1;X65879
   1 Drosophila pseudoobscura Rh3 <>[Genetics132(1),193-204'92
MEYHNVSS--V-LGN-VSSV-----------LRPDA-RL-------S---
------------------A--E--SR---------LLGWNVPPDELRHIP
EH-WLIYP-EPPESMNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTP
SNILVINLAFCDFMMM-I-KTPIFI-YNSFH-QGYALGHLGCQIFGVIGS
YTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMIIFIYLYATPW
-VVACYTESWGR-----FVPEGYL---TSCTFDYLTDN--FDTRLFVACI
FFFSFVCPTTMITYYYSQIVGHVFSHEKAL--------------------
--------------------------------------------------
-------------------------------RDQ------A---------
------------K----------------------KMNVDSL---RSNVD
KSKEAAEIRIAKAAITICFLFFASWTPYGVMSLIGAFGDKTL--LTPG-A
TMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLA--ISEK-AP-ES
-RAAIS-TSTT----------------Q----------------------
--------------------------------------------------
-------------------EQQQTTAA
*
>P1;M17730
   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
MEPLCNAS-EP--------P-----------LRPEA-RS-----------
------------------S-GNGDLQ---------FLGWNVPPDQIQYIP
EH-WLTQL-EPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTP
SNMFVLNLAVFDLIMC-L-KAPIFN-SFHRG-FAIYLGNTWCQIFASIGS
YSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW
-VVLPLTQFWDR-----FVPEGYL---TSCSFDYLSDN--FDTRLFVGTI
FFFSFVCPTLMILYYYSQIVGHVFSHEKAL--------------------
--------------------------------------------------
-------------------------------REQ------A---------
------------K----------------------KMNVESL---RSNVD
KSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSL--LTQG-A
TMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLG--VNEK-SG-EI
-SSAQS-TT-T----------------Q----------------------
--------------------------------------------------
-------------------EQQQTTAA
*
>P1;X65880
   1 Drosophila pseudoobscura Rh4 <>[Genetics132(1),193-204'92
MDALCNAS-EP--------P-----------LRPEA-RM-------S---
------------------S-GSDELQ---------FLGWNVPPDQIQYIP
EH-WLTQL-EPPASMHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTP
SNMFVLNLAVFDLIMC-L-KAPIFI-YNSFH-RGFALGNTWCQIFASIGS
YSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNIIIWLYCTPW
-VVLPLTQFWDR-----FVPEGYL---TSCSFDYLSDN--FDTRLFVGTI
FLFSFVVPTLMILYYYSQIVGHVFNHEKAL--------------------
--------------------------------------------------
-------------------------------REQ------A---------
------------K----------------------KMNVESL---RSNVD
KSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSL--LTPG-A
TMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLG--VNEK-SG-EA
-SSAQS-TTTQ----------------E----------------------
--------------------------------------------------
-------------------QTQQTSAA
*
>P1;D50584
   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
MTNATGPQ-MAYYGA-ASMD-----------FG-----Y-------P---
------------------E-G---VS----------IVDFVRPEIKPYVH
QH-WYNYP-PVNPMWHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTP
ANILVVNLALSDLIMLTT-NVPFFT-YNCFSGGVWMFSPQYCEIYACLGA
ITGVCSIWLLCMISFDRYNIICNGFNG-PKLTTGKAVVFALISWVIAIGC
-ALPPF-FGWGN-----YILEGIL---DSCSYDYLTQD--FNTFSYNIFI
FVFDYFLPAAIIVFSYVFIVKAIFAHEAAM--------------------
--------------------------------------------------
-------------------------------RAQ------A---------
------------K----------------------KMNVSTL---RSNE-
ADAQRAEIRIAKTALVNVSLWFICWTPYALISLKGVMGDTSG--ITPL-V
STLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFC--VHET-ET-KS
-NDDSQ-SNS----------------------------------------
--------------------------------------------------
--------------------TVAQDKA
*
>P1;D50583
   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
MANVTGPQ-MAFYGS-GAAT-----------FG-----Y-------P---
------------------E-G---MT----------VADFVPDRVKHMVL
DH-WYNYP-PVNPMWHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTP
ANMLIVNLALSDLIMLTT-NFPPFC-YNCFSGGRWMFSGTYCEIYAALGA
ITGVCSIWTLCMISFDRYNIICNGFNG-PKLTQGKATFMCGLAWVISVGW
-SLPPF-FGWGS-----YTLEGIL---DSCSYDYFTRD--MNTITYNICI
FIFDFFLPASVIVFSYVFIVKAIFAHEAAM--------------------
--------------------------------------------------
-------------------------------RAQ------A---------
------------K----------------------KMNVTNL---RSNE-
AETQRAEIRIAKTALVNVSLWFICWTPYAAITIQGLLGNAEG--ITPL-L
TTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFC--VHEK-DP-ND
-VEENQ-SSN----------------------------------------
--------------------------------------------------
--------------------TQTQEKS
*
>P1;K02320
   1 D.melanogaster opsin <>[Cell40,851-858'85]
MESFAVAA----------AQ-----------LGPHF-AP-------L---
---------------------SN-GS----------VVDKVTPDMAHLIS
PY-WNQFP-AMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTP
ANLLVINLAISDFGIMIT-NTPMMG-INLYF-ETWVLGPMMCDIYAGLGS
AFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLAL-------------
---------GKM-----YVPEGNL---TSCGIDYLERD--WNPRSYLIFY
SIFVYYIPLFLICYSYWFIIAAVSAHEKAM--------------------
--------------------------------------------------
-------------------------------REQ------A---------
------------K----------------------KMNVKSL---RSSED
-AEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFK-FEG--LTPL-N
TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV--FGKVDDGK-S
-SD-AQ-SQAT---------------------------------------
--------------------------------------------------
-------------------ASEAESKA
*
>P1;K02315
   1 D.melanogaster ninaE <>[Cell40,839-850'85]
MESFAVAA----------AQ-----------LGPHF-AP-------L---
---------------------SN-GS----------VVDKVTPDMAHLIS
PY-WNQFP-AMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTP
ANLLVINLAISDFGIMIT-NTPMMG-INLYF-ETWVLGPMMCDIYAGLGS
AFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKIAYIWFMSSIW
-CLAPA-FGWSR-----YVPEGNL---TSCGIDYLERD--WNPRSYLIFY
SIFVYYIPLFLICYSYWFIIAAVSAHEKAM--------------------
--------------------------------------------------
-------------------------------REQ------A---------
------------K----------------------KMNVKSL---RSSED
-AEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFK-FEG--LTPL-N
TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV--FGKVDDGK-S
-SD-AQ-SQAT---------------------------------------
--------------------------------------------------
-------------------ASEAESKA
*
>P1;X65877
   1 Drosophila pseudoobscura ninaE <>[Genetics132(1),193-204'
MDSFAAVA----------TQ-----------LGPQF-AA-------P---
---------------------SN-GS----------VVDKVTPDMAHLIS
PY-WDQFP-AMDPIWAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTP
ANLLVINLAISDFGIMIT-NTPMMG-INLYF-ETWVLGPMMCDIYAGLGS
AFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKIAYIWFMSTIW
CCLAPV-FGWSR-----YVPEGNL---TSCGIDYLERD--WNPRSYLIFY
SIFVYYIPLFLICYSYWFIIAAVSAHEKAM--------------------
--------------------------------------------------
-------------------------------REQ------A---------
------------K----------------------KMNVKSL---RSSED
-ADKSAEGKLAKVALVTISLWFMAWTPYLVINCMGLFK-FEG--LTPL-N
TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV--FGKVDDGK-S
-SE-AQ-SQAT---------------------------------------
--------------------------------------------------
-------------------TSEAESKA
*
>P1;M12896
   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
MERSHLPE-TPFDL----AH-----------SGPRF-QA-------Q---
------------------S-SGN-GS----------VLDNVLPDMAHLVN
PY-WSRFA-PMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTP
ANLLVLNLAFSDFCMMAS-QSPVMI-INFYY-ETWVLGPLWCDIYAGCGS
LFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKILFIWMMAVFW
-TVMPL-IGWSA-----YVPEGNL---TACSIDYMTRM--WNPRSYLITY
SLFVYYTPLFLICYSYWFIIAAVAAHEKAM--------------------
--------------------------------------------------
-------------------------------REQ------A---------
------------K----------------------KMNVKSL---RSSED
-CDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLFK-IDG--LTPL-T
TIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCV--FGNTDEPK-P
-DAPAS-DTET---------------------------------------
--------------------------------------------------
-------------------TSEADSKA
*
>P1;X65878
   1 Drosophila pseudoobscura Rh2 <>[Genetics132(1),193-204'92
MERSLLPE-PPLAM----AL-----------LGPRF-EA-------Q---
------------------T-GGN-RS----------VLDNVLPDMAPLVN
PH-WSRFA-PMDPTMSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTP
ANLLVLNLAFSDFCMMAS-QSPVMI-INFYY-ETWVLGPLWCDIYAACGS
LFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKIAFIWMMAVFW
-TIMPL-IGWSS-----YVPEGNL---TACSIDYMTRQ--WNPRSYLITY
SLFVYYTPLFMICYSYWFIIATVAAHEKAM--------------------
--------------------------------------------------
-------------------------------RDQ------A---------
------------K----------------------KMNVKSL---RSSED
-CDKSAENKLAKVALTTISLWFMAWTPYLIICYFGLFK-IDG--LTPL-T
TIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCV--CGTTDEPK-P
-DAPPS-DTET---------------------------------------
--------------------------------------------------
-------------------TSEAESKD
*
>P1;U26026
   1 Apis mellifera long-wavelength rhodopsin <>[]
MIAVSGPS-YE-A-----FS-----------YGGQ--AR-------F---
---------------------NN-QT----------VVDKVPPDMLHLID
AN-WYQYP-PLNPMWHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTP
SNLFVINLAISNFLMMFC-MSPPMV-INCYY-ETWVLGPLFCQIYAMLGS
LFGCGSIWTMTMIAFDRYNVIVKGLSG-KPLSINGALIRIIAIWLFSLGW
-TIAPM-FGWNR-----YVPEGNM---TACGTDYFNRG--LLSASYLVCY
GIWVYFVPLFLIIYSYWFIIQAVAAHEKNM--------------------
--------------------------------------------------
-------------------------------REQ------A---------
------------K----------------------KMNVASL---RSSEN
-QNTSAECKLAKVALMTISLWFMAWTPYLVINFSGIFN-LVK--ISPL-F
TIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLA--CAAEPSS-DA
-VSTTS-GTTT----------------V----------------------
--------------------------------------------------
-------------------TDNEKSNA
*
>P1;L03781
   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
MANQLSYS-SL-G-----WP-----------YQ-----------------
---------------------PN-AS----------VVDTMPKEMLYMIH
EH-WYAFP-PMNPLWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTP
TNLLVVNLAFSDFCMMAF-MMPTMT-SNCFA-ETWILGPFMCEVYGMAGS
LFGCASIWSMVMITLDRYNVIVRGMAA-APLTHKKATLLLLFVWIWSGGW
-TILPF-FGWSR-----YVPEGNL---TSCTVDYLTKD--WSSASYVVIY
GLAVYFLPLITMIYCYFFIVHAVAEHEKQL--------------------
--------------------------------------------------
-------------------------------REQ------A---------
------------K----------------------KMNVASL---RANAD
QQKQSAECRLAKVAMMTVGLWFMAWTPYLIISWAGVFSSGTR--LTPL-A
TIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLA--CGSGESGSDV
-KSEAS-ATTT----------------M----------------------
--------------------------------------------------
------------------EEKPKIPEA
*
>P1;X07797
   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
MVESTTLV-NQ-T-------------------------------------
--------------------------------------WWYNP--TVDIH
PH-WAKFD-PIPDAVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTP
ANMFIINLAMSDLSFSAINGFPLKT-ISAFM-KKWIFGKVACQLYGLLGG
IFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIFVWMWSIVW
-SVGPV-FNWGA-----YVPEGIL---TSCSFDYLSTD--PSTRSFILCM
YFCGFMLPIIIIAFCYFNIVMSVSNHEKEM--------------------
--------------------------------------------------
-------------------------------AAM------A---------
------------K----------------------RLNAKEL---RKA--
QAGASAEMKLAKISMVIITQFMLSWSPYAIIALLAQFGPAEW--VTPY-A
AELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKECED
-ANDAE-EEVV---------------ASERGGE--SRDAAQMKEMMAMMQ
KMQAQQAAYQPPPPPQGYPPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGY
PPQGAPPQVEAPQGAPPQGVDNQAYQA
*
>P1;X70498
   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
MGRDLR-D-NE-T-------------------------------------
--------------------------------------WWYNP--SIVVH
PH-WREFD-QVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTP
ANMFIINLAFSDFTFSLVNGFPLMT-ISCFL-KKWIFGFAACKVYGFIGG
IFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLW
-AIGPI-FGWGA-----YTLEGVL---CNCSFDYISRD--STTRSNILCM
FILGFFGPILIIFFCYFNIVMSVSNHEKEM--------------------
--------------------------------------------------
-------------------------------AAM------A---------
------------K----------------------RLNAKEL---RKA--
QAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEW--VTPY-A
AQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETED
-DKDAE-TEIP---------------AGESSDAAPSADAAQMKEMMAMMQ
KMQQQQAAYPPQG----YAPPPQGYPPQGYPPQGYPPQGYPPQGY---PP
PPQGAPPQG-APPAAPPQGVDNQAYQA
*
>P1;L21195
   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
MMDVNSSGRPDLY-G----HLRS-FLLPEVGRGLPDLSPDGG----A---
D---------------PVAGSWA-PHLLSEVTASPAPTWDAPPDNA--SG
CGEQINYG----RVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQP
SNYLIVSLALADLSVAVA-VMPFVSVTDLIG-GKWIFGHFFCNVFIAMDV
MCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI
-TLPPL-FGWAQ-----NVNDDKV---CLISQD----------FGYTIYS
TAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFP--------------
--------------------------------------RVE---------
-----PDSVI-----------ALNG-IVKLQKEV------E---------
------------E----------------------CANLSRLLKHERKN-
ISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
ERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQ----C-QYRNINRK-
LSAAGMH-EALKLAERPERPEFVLQNAD----------------------
--------------------------------------------------
------------------YCRKKGHDS
*
>P1;L15228
   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
MPHLLSG-FLE---------------------------------------
------------------------------VTASPAPTWDAPPDNV--SG
CGEQINYG----RVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQP
SNYLIVSLALADLSVAVA-VMPFVSVTDLIG-GKWIFGHFFCNVFIAMDV
MCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI
-TLPPL-FGWAQ-----NVNDDKV---CLISQD----------FGYTIYS
TAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFP--------------
--------------------------------------RVQ---------
-----PESVI-----------SLNG-VVKLQKEV------E---------
------------E----------------------CANLSRLLKHERKN-
ISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
ERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQ----C-QYRNINRK-
LSAAGMH-EALKLAERPERSEFVLQNSD----------------------
--------------------------------------------------
------------------HCGKKGHDT
*
>P1;A47425
 serotonin receptor 5HT-7 - rat
MPHLLSG-FLE---------------------------------------
------------------------------VTASPAPTWDAPPDNV--SG
CGEQINYG----RVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQP
SNYLIVSLALADLSVAVA-VMPFVSVTDLIG-GKWIFGHFFCNVFIAMDV
MCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASI
-TLPPL-FGWAQ-----NVNDDKV---CLISQD----------FGYTIYS
TAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFP--------------
--------------------------------------RVQ---------
-----PESVI-----------SLNG-VVKLQKEV------E---------
------------E----------------------CANLSRLLKHERKN-
ISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
ERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQ----C-QYRNINRK-
LSAAGMH-EALKLAERPERSEFVLQNSD----------------------
--------------------------------------------------
------------------HCGKKGHDT
*
>P1;M83181
   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
MDVLSPG-QGNNTTS---PP-----------------AP-------F---
-----------------ET-GGN-TTG-------------IS--------
-----DVT----VSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNV
ANYLIGSLAVTDLMVSVL-VLPMAA-LYQVL-NKWTLGQVTCDLFIALDV
LCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI
-SIPPM-LGWRT-----PEDRSDPD-ACTISKD----------HGYTIYS
TFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT---------
------------------------------RHGASPAPQPKKSVNGESGS
RNWRL--GVESKAGGALCANGAVRQGDDGAA-------------------
-----LEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKR-
KMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSC-HMPTL-L
GAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK----C-K--------
--------------------------------------------------
--------------------------------------------------
-----------------------FCRQ
*
>P1;A35181
 serotonin receptor class 1A - rat
MDVFSFG-QGNNTTA---SQ-----------------EP-------F---
-----------------GT-GGN-VTS-------------IS--------
-----DVT----FSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNV
ANYLIGSLAVTDLMVSVL-VLPMAA-LYQVL-NKWTLGQVTCDLFIALDV
LCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLI
-SIPPM-LGWRT-----PEDRSDPD-ACTISKD----------HGYTIYS
TFGAFYIPLLLMLVLYGRIFRAARFRIRKTVRKVEKKGAGT---------
------------------------------SLGTSSAPPPKKSLNGQPGS
GDWRR--CAENRAVGTPCTNGAVRQGDDEAT-------------------
-----LEVIEVHRVGNSKEHLPLPSESGSNSYAPACLERKNERNAEAKR-
KMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSC-HMPAL-L
GAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK----C-K--------
--------------------------------------------------
--------------------------------------------------
-----------------------FCRR
*
>P1;L06803
   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFG-DLALDVARMGGLASTPSGLRSTGLTTPGLSPTGLVTSDFNDS
YGLTGQFINGSHSSRSRDNASAN-DTSATNM--TDDRYWSLT--------
-----VYS----HEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNV
ANYLILSLAVADLMVAVL-VMPLSV-VSEIS-KVWFLHSEVCDMWISVDV
LCCTASILHLVAIAMDRYWAVTSIDYI-RRRSARRILLMIMVVWIVALFI
-SIPPL-FGWRD-----PNNDPDKTGTCIISQD----------KGYTIFS
TVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASP
KTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKN-RAKK--
----LPENAN-----------GVNS-NSSSS-ERLKQIQIETAEAFANGC
AEEASIAML-ERQCNNGKKIS-----------------SNDTPYSRTRE-
KLELKRERKAARTLAIITGAFLICWLPFFIIALIGPFVDPEG--IPPF-A
RSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILF----G-K-Y------
--------------------------------------------------
--------------------------------------------------
----------------------RRGHR
*
>P1;A47174
 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFG-DLALDVARMGGLASTPSGLRSTGLTTPGLSPTGLVTSDFNDS
YGLTGQFINGSHSSRSRDNASAN-DTSATNM--TDDRYWSLT--------
-----VYS----HEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNV
ANYLILSLAVADLMVAVL-VMPLSV-VSEIS-KVWFLHSEVCDMWISVDV
LCCTASILHLVAIAMDRYWAVTSIDYI-RRRSARRILLMIMVVWIVALFI
-SIPPL-FGWRD-----PNNDPDKTGTCIISQD----------KGYTIFS
TVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASP
KTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKN-RAKK--
----LPENAN-----------GVNS-NSSSS-ERLKQIQIETAEAFANGC
AEEASIAML-ERQCNNGKKIS-----------------SNDTPYSRTRE-
KLELKRERKAARTLAIITGAFLICWLPFFIIALIGPFVDPEG--IPPF-A
RSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILF----G-K-Y------
--------------------------------------------------
--------------------------------------------------
----------------------RRGHR
*
>P1;X95604
   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
MEGAEGQ-EE-LDWEALYLRL--P--LQNCSWNSTGWEP-----------
--------------------NWN-VTVV-----PNTTWWQAS-------A
PFDT-PAA----LVRAAAKAVVLGLLILATVVGNVFVIAAILLERHLRSA
ANNLILSLAVADLLVACL-VMPLGA-VYEVV-QRWTLGPELCDMWTSGDV
LCCTASILHLVAIALDRYWAVTNIDYI-HASTAKRVGMMIACVWTVSFFV
-CIAQL-LGWKDPDWNQRVSEDLR---CVVSQD----------VGYQIFA
TASSFYVPVLIILILYWRIYQTARKRIRRRRGATARGGVGPP--------
-----PVPAGGALVAGGGSGGIAAAVVAVIGRPLPTISETTTT-GF----
----T--NVS-----------SNNT-SP----EK------Q---------
------------SCANGLEADPPTTGYG----AVAAAYYPSLVRRKPKE-
AADSKRERKAAKTLAIITGAFVACWLPFFVLAILVPTCD-CE--VSPV-L
TSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLC----G-R-RV-----
--------------------------------------------------
--------------------------------------------------
--------------------RRRRAPQ
*
