35 675
L21195     ---------- MMDVNSSGRP DLYGHLRSFL LPEVGRGLPD LSPDGGADPV
L15228     ---------- ---------- ---------- ---------- -----MPHLL
A47425     ---------- ---------- ---------- ---------- -----MPHLL
M83181     ---------- -------MDV LSPGQGNNTT SPPAPFETGG --NTTGISDV
A35181     ---------- -------MDV FSFGQGNNTT ASQEPFGTGG --NVTSISDV
L06803     MANFTFGDLA LDVARMGGLA STPSGLRSTG LTTPGLSPTG LVTSDFNDSY
A47174     MANFTFGDLA LDVARMGGLA STPSGLRSTG LTTPGLSPTG LVTSDFNDSY
X95604     ---------- --------ME GAEGQEELDW EALYLRLPLQ -NCSWNSTGW
M13299     ---------- ---------- ------MRKM SEEEFYLFKN -----ISSVG
L11864     ---------- ---------- ----MKQVPE FHEDFYIPIP LDINNLSAYS
M92038     ---------- ---------- ------MNGT EGINFYVPMS --NKTGVVRS
A45229     ---------- ---------- ------MNGT EGKNFYVPMS --NRTGLVRS
B45229     ---------- ---------- ------MNGT EGNNFYVPLS --NRTGLVRS
M63632     ---------- ---------- ------MNGT EGDNFYVPFS --NKTGLARS
U22180     ---------- ---------- ------MNGT EGPNFYVPFS --NITGVVRS
S75720     ---------- ---------- ---------- -----MSSNS SQAPPNGTPG
M92036     ---------- ---MTEAWNV AVFAARRSRD DDDTTRGSVF TYTNTNNTRG
M62903     ---------- -----MAAWE AAFAARRRHE EEDTTRDSVF TYTNSNNTRG
K03494     ---------- --MAQQWSLQ RLAGRHPQDS YEDSTQSSIF TYTNSNSTRG
Z68193     ---------- --MAQQWSLQ RLAGRHPQDS YEDSTQSSIF TYTNSNSTRG
M17730     ---------- MEPLCNASEP PLRPEARSSG NGDLQFLGWN -VPPDQIQYI
X65880     ---------M DALCNASEPP LRPEARMSSG SDELQFLGWN -VPPDQIQYI
M17718     ------MESG NVSSSLFGNV STALRPEARL SAETRLLGWN -VPPEELRHI
X65879     -------MEY HNVSSVLGNV SSVLRPDARL SAESRLLGWN -VPPDELRHI
X07797     ---------- ---------- -------MVE STTLVNQTWW YNPTVD---I
X70498     ---------- ---------- --------MG RDLRDNETWW YNPSIVVH--
D50584     ---------- -MTNATGPQM AYYGAASMDF GYPEGVSIVD FVRPEIKPYV
D50583     ---------- -MANVTGPQM AFYGSGAATF GYPEGMTVAD FVPDRVKHMV
L03781     ---------- --------MA NQLSYSSLGW PYQPNASVVD TMPKEMLYMI
U26026     ---------- --MIAVSGPS YEAFSYGGQA RFNNQTVVDK -VPPDMLHLI
X65877     ---------- -----MDSFA AVATQLGPQF AAPSNGSVVD KVTPDMAHLI
K02320     ---------- -----MESFA VAAAQLGPHF APLSNGSVVD KVTPDMAHLI
K02315     ---------- -----MESFA VAAAQLGPHF APLSNGSVVD KVTPDMAHLI
M12896     --------ME RSHLPETPFD LAHSGPRFQA QSSGNGSVLD NVLPDMAHLV
X65878     -------MER SLLPEPPLAM ALLGPRFEAQ TGGNRSVLDN -VLPDMAPLV

AGSWAPHLLS EVTASPAPT- ---------- ----WDAPPD NASGCGEQIN YGRVEKVVIG
SGFL------ EVTASPAPT- ---------- ----WDAPPD NVSGCGEQIN YGRVEKVVIG
SGFL------ EVTASPAPT- ---------- ----WDAPPD NVSGCGEQIN YGRVEKVVIG
TVSY------ ---------- ---------- ---------- ---------- -----QVITS
TFSY------ ---------- ---------- ---------- ---------- -----QVITS
GLTGQFINGS HSSRSRDNAS ANDTSATNMT DDRYW----- ------SLTV YSHEHLVLTS
GLTGQFINGS HSSRSRDNAS ANDTSATNMT DDRYW----- ------SLTV YSHEHLVLTS
EPNW------ NVTVVPNTT- ---------- ----W----- WQASAPFDTP AALVRAAAKA
PWDG------ PQY-HIAPV- ---------- ----W----- ---------- ----AFYLQA
PFLV------ PQDHLGNQG- ---------- ----I----- ---------- -----FMAMS
PFEY------ PQYYLAEP-- ---------- ----W----- ---------- ----KYRLVC
PFEY------ PQYYLAEP-- ---------- ----W----- ---------- ----QFKILA
PFEY------ PQYYLAEP-- ---------- ----W----- ---------- ----QFKLLA
PYEY------ PQYYLAEP-- ---------- ----W----- ---------- ----KYSALA
PFEQ------ PQYYLAEP-- ---------- ----W----- ---------- ----QFSMLA
PFDG------ PQWPYQAPQ- ---------- ----S----- ---------- ----TYVGVA
PFEG------ PNY-HIAPR- ---------- ----W----- ---------- ----VYNLVS
PFEG------ PNY-HIAPR- ---------- ----W----- ---------- ----VYNLTS
PFEG------ PNY-HIAPR- ---------- ----W----- ---------- ----VYHLTS
PFEG------ PNY-HIAPR- ---------- ----W----- ---------- ----VYHLTS
PEHW------ LTQLEPPAS- ---------- ----M----- ---------- -----HYMLG
PEHW------ LTQLEPPAS- ---------- ----M----- ---------- -----HYMLG
PEHW------ LTYPEPPES- ---------- ----M----- ---------- -----NYLLG
PEHW------ LIYPEPPES- ---------- ----M----- ---------- -----NYLLG
HPHW------ AKFDPIPDA- ---------- ----V----- ---------- -----YYSVG
-PHW------ REFDQVPDA- ---------- ----V----- ---------- -----YYSLG
HQHW------ YNYPPVNPM- ---------- ----W----- ---------- -----HYLLG
LDHW------ YNYPPVNPM- ---------- ----W----- ---------- -----HYLLG
HEHW------ YAFPPMNPL- ---------- ----W----- ---------- -----YSILG
DANW------ YQYPPLNPM- ---------- ----W----- ---------- -----HGILG
SPYW------ DQFPAMDPI- ---------- ----W----- ---------- -----AKILT
SPYW------ NQFPAMDPI- ---------- ----W----- ---------- -----AKILT
SPYW------ NQFPAMDPI- ---------- ----W----- ---------- -----AKILT
NPYW------ SRFAPMDPM- ---------- ----M----- ---------- -----SKILG
NPHW------ SRFAPMDPT- ---------- ----M----- ---------- -----SKILG

SILTLITLLT IAGNCLVVIS VCFVKKLRQP SNYLIVSLAL ADLSV-AVAV MPFVSVTDLI
SILTLITLLT IAGNCLVVIS VSFVKKLRQP SNYLIVSLAL ADLSV-AVAV MPFVSVTDLI
SILTLITLLT IAGNCLVVIS VSFVKKLRQP SNYLIVSLAL ADLSV-AVAV MPFVSVTDLI
LLLGTLIFCA VLGNACVVAA IALERSLQNV ANYLIGSLAV TDLMV-SVLV LPMAALYQVL
LLLGTLIFCA VLGNACVVAA IALERSLQNV ANYLIGSLAV TDLMV-SVLV LPMAALYQVL
VILGLFVLCC IIGNCFVIAA VMLERSLHNV ANYLILSLAV ADLMV-AVLV MPLSVVSEIS
VILGLFVLCC IIGNCFVIAA VMLERSLHNV ANYLILSLAV ADLMV-AVLV MPLSVVSEIS
VVLGLLILAT VVGNVFVIAA ILLERHLRSA ANNLILSLAV ADLLV-ACLV MPLGAVYEVV
AFMGTVFLIG FPLNAMVLVA TLRYKKLRQP LNYILVNVSF GGFLLCIFSV FPVFVASCN-
VFMFFIFIGG ASINILTILC TIQFKKLRSH LNYILVNLSI ANLFV-AIFG SPLSFYSFFN
CYIFFLISTG LPINLLTLLV TFKHKKLRQP LNYILVNLAV ADLFM-ACFG FTVTFYTAWN
LYLFFLMSMG LPINGLTLVV TAQHKKLRQP LNFILVNLAV AGTIM-VCFG FTVTFYTAIN
VYMFFLICLG LPINGLTLIC TAQHKKLRQP LNFILVNLAV AGAIM-VCFG FTVTFYTAIN
AYMFFLILVG FPVNFLTLFV TVQHKKLRTP LNYILLNLAM ANLFM-VLFG FTVTMYTSMN
AYMFLLIVLG FPINFLTLYV TVQHKKLRTP LNYILLNLAV ADLFM-VFGG FTTTLYTSLH
VLMGTVVACA SVVNGLVIVV SICYKKLRSP LNYILVNLAV ADLLV-TLCG SSVSLSNNIN
FFMIIVVIAS CFTNGLVLVA TAKFKKLRHP LNWILVNLAF VDLVE-TLVA STISVFNQIF
VWMIFVVAAS VFTNGLVLVA TWKFKKLRHP LNWILVNLAV ADLGE-TVIA STISVINQIS
VWMIFVVIAS VFTNGLVLAA TMKFKKLRHP LNWILVNLAV ADLAE-TVIA STISVVNQVY
VWMIFVVTAS VFTNGLVLAA TMKFKKLRHP LNWILVNLAV ADLAE-TVIA STISIVNQVS
VFYIFLFCAS TVGNGMVIWI FSTSKSLRTP SNMFVLNLAV FDLIM--CLK APIF--NSFH
VFYIFLFFAS TLGNGMVIWI FSTSKSLRTP SNMFVLNLAV FDLIM--CLK APIFIYNSFH
TLYIFFTLMS MLGNGLVIWV FSAAKSLRTP SNILVINLAF CDFMM--MVK TPIFIYNSFH
TLYIFFTVIS MIGNGLVMWV FSAAKSLRTP SNILVINLAF CDFMM--MIK TPIFIYNSFH
IFIGVVGIIG ILGNGVVIYL FSKTKSLQTP ANMFIINLAM SDLSFSAING FPLKTISAFM
IFIGICGIIG CGGNGIVIYL FTKTKSLQTP ANMFIINLAF SDFTFSLVNG FPLMTISCFL
VIYLFLGTVS IFGNGLVIYL FNKSAALRTP ANILVVNLAL SDLIM-LTTN VPFFTYNCFS
VVYLFLGVIS IAGNGLVIYL YMKSQALKTP ANMLIVNLAL SDLIM-LTTN FPPFCYNCFS
VAMIILGIIC VLGNGMVIYL MMTTKSLRTP TNLLVVNLAF SDFCM-MAFM MPTMTSNCFA
FVIGMLGFVS AMGNGMVVYI FLSTKSLRTP SNLFVINLAI SNFLM-MFCM SPPMVINCYY
AYMIIIGMIS WCGNGVVIYI FATTKSLRTP ANLLVINLAI SDFGI-MITN TPMMGINLYF
AYMIMIGMIS WCGNGVVIYI FATTKSLRTP ANLLVINLAI SDFGI-MITN TPMMGINLYF
AYMIMIGMIS WCGNGVVIYI FATTKSLRTP ANLLVINLAI SDFGI-MITN TPMMGINLYF
LFTLAIMIIS CCGNGVVVYI FGGTKSLRTP ANLLVLNLAF SDFCM-MASQ SPVMIINFYY
LFTLVILIIS CCGNGVVVYI FGGTKSLRTP ANLLVLNLAF SDFCM-MASQ SPVMIINFYY

GGKWI--FGH FFCNVFIAMD VMCCTASIMT LCVISIDRYL GITRPLTYPV RQNGKCMAKM
GGKWI--FGH FFCNVFIAMD VMCCTASIMT LCVISIDRYL GITRPLTYPV RQNGKCMAKM
GGKWI--FGH FFCNVFIAMD VMCCTASIMT LCVISIDRYL GITRPLTYPV RQNGKCMAKM
-NKWT--LGQ VTCDLFIALD VLCCTSSILH LCAIALDRYW AITDPIDYVN KRTPRRAAAL
-NKWT--LGQ VTCDLFIALD VLCCTSSILH LCAIALDRYW AITDPIDYVN KRTPRRAAAL
-KVWF--LHS EVCDMWISVD VLCCTASILH LVAIAMDRYW AVTS-IDYIR RRSARRILLM
-KVWF--LHS EVCDMWISVD VLCCTASILH LVAIAMDRYW AVTS-IDYIR RRSARRILLM
-QRWT--LGP ELCDMWTSGD VLCCTASILH LVAIALDRYW AVTN-IDYIH ASTAKRVGMM
-GYFV--FGR HVCALEGFLG TVAGLVTGWS LAFLAFERYI VICKPFGN-F RFSSKHALTV
-RYFI--FGA TACKIEGFLA TLGGMVGLWS LAVVAFERWL VICKPLGN-F TFKTPHAIAG
-GYFV--FGP VGCAVEGFFA TLGGQVALWS LVVLAIERYI VVCKPMGN-F RFSATHAMMG
-GYFV--LGP TGCAVEGFMA TLGGEVALWS LVVLAIERYI VVCKPMGS-F KFSSSHAFAG
-GYFA--LGP TGCAVEGFMA TLGGEVALWS LVVLAIERYI VVCKPMGS-F KFSSTHASAG
-GYFV--FGP TMCSIEGFFA TLGGEVALWS LVVLAIERYI VICKPMGN-F RFGNTHAIMG
-GYFV--FGP TGCNLEGFFA TLGGEIGLWS LVVLAIERYV VVCKPMSN-F RFGENHAIMG
-GFFV--FGR RMCELEGFMV SLTGIVGLWS LAILALERYV VVCKPLGD-F QFQRRHAVSG
-GYFI--LGH PLCVIEGYVV SSCGITGLWS LAIISWERWF VVCKPFGN-I KFDSKLAIIG
-GYFI--LGH PMCVVEGYTV SACGITALWS LAIISWERWF VVCKPFGN-I KFDGKLAVAG
-GYFV--LGH PMCVLEGYTV SLCGITGLWS LAIISWERWM VVCKPFGN-V RFDAKLAIVG
-GYFV--LGH PMCVLEGYTV SLCGITGLWS LAIISWERWL VVCKPFGN-V RFDAKLAIVG
-RGFAIYLGN TWCQIFASIG SYSGIGAGMT NAAIGYDRYN VITKPMN--R NMTFTKAVIM
-RGFA--LGN TWCQIFASIG SYSGIGAGMT NAAIGYDRYN VITKPMN--R NMTFTKAVIM
-QGYA--LGH LGCQIFGIIG SYTGIAAGAT NAFIAYDRFN VITRPMEG-- KMTHGKAIAM
-QGYA--LGH LGCQIFGVIG SYTGIAAGAT NAFIAYDRYN VITRPMEG-- KMTHGKAIAM
-KKWI--FGK VACQLYGLLG GIFGFMSINT MAMISIDRYN VIGRPMAASK KMSHRRAFLM
-KKWI--FGF AACKVYGFIG GIFGFMSIMT MAMISIDRYN VIGRPMAASK KMSHRRAFIM
GGVWM--FSP QYCEIYACLG AITGVCSIWL LCMISFDRYN IICNGFNG-P KLTTGKAVVF
GGRWM--FSG TYCEIYAALG AITGVCSIWT LCMISFDRYN IICNGFNG-P KLTQGKATFM
-ETWI--LGP FMCEVYGMAG SLFGCASIWS MVMITLDRYN VIVRGMAA-A PLTHKKATLL
-ETWV--LGP LFCQIYAMLG SLFGCGSIWT MTMIAFDRYN VIVKGLSG-K PLSINGALIR
-ETWV--LGP MMCDIYAGLG SAFGCSSIWS MCMISLDRYQ VIVKGMAG-R PMTIPLALGK
-ETWV--LGP MMCDIYAGLG SAFGCSSIWS MCMISLDRYQ VIVKGMAG-R PM--------
-ETWV--LGP MMCDIYAGLG SAFGCSSIWS MCMISLDRYQ VIVKGMAG-R PMTIPLALGK
-ETWV--LGP LWCDIYAGCG SLFGCVSIWS MCMIAFDRYN VIVKGING-T PMTIKTSIMK
-ETWV--LGP LWCDIYAACG SLFGCVSIWS MCMIAFDRYN VIVKGING-T PMTIKTSIMK

ILSVWLLSAS I-TLPPLFG- W-----AQNV NDDK-VCLIS QDF------- ---GYTIYST
ILSVWLLSAS I-TLPPLFG- W-----AQNV NDDK-VCLIS QDF------- ---GYTIYST
ILSVWLLSAS I-TLPPLFG- W-----AQNV NDDK-VCLIS QDF------- ---GYTIYST
ISLTWLIGFL I-SIPPMLG- WRTPE-DRSD PDA---CTIS KDH------- ---GYTIYST
ISLTWLIGFL I-SIPPMLG- WRTPE-DRSD PDA---CTIS KDH------- ---GYTIYST
IMVVWIVALF I-SIPPLFG- WRD---PNND PDKTGTCIIS QDK------- ---GYTIFST
IMVVWIVALF I-SIPPLFG- WRD---PNND PDKTGTCIIS QDK------- ---GYTIFST
IACVWTVSFF V-CIAQLLG- WKDPDWNQRV SEDL-RCVVS QDV------- ---GYQIFAT
VLATWTIGIG V-SIPPFFG- W-----SRFI PEGL-QCSCG PDWYTVGTKY RSESYTWFLF
CILPWISALA A-SLPPLFG- W-----SRYI PEGL-QCSCG PDWYTTNNKY NNESYVMFLF
IAFTWVMAFS C-AAPPLFG- W-----SRYM PEGM-QCSCG PDYYTHNPDY HNESYVLYMF
IAFTWVMALA C-AAPPLFG- W-----SRYI PEGM-QCSCG PDYYTLNPDY NNESYVIYMF
IAFTWVMAMA C-AAPPLVG- W-----SRYI PEGI-QCSCG PDYYTLNPEY NNESYVLYMF
VAFTWIMALA C-AAPPLVG- W-----SRYI PEGM-QCSCG PDYYTLNPNF NNESYVVYMF
VAFTWVMALA C-AAPPLVG- W-----SRYI PEGM-QCSCG IDYYTLKPEV NNESFVIYMF
CAFTWGWALL W-SAPPLLG- W-----SSYV PEGL-RTSCG PNWYT--GGS NNNSYILSLF
IVFSWVWAWG W-SAPPIFG- W-----SRYW PHGL-KTSCG PDVFSGSVEL GCQSFMLTLM
ILFSWLWSCA W-TAPPIFG- W-----SRYW PHGL-KTSCG PDVFSGSSDP GVQSYMVVLM
IAFSWIWAAV W-TAPPIFG- W-----SRYW PHGL-KTSCG PDVFSGSSYP GVQSYMIVLM
IAFSWIWSAV W-TAPPIFG- W-----SRYW PHGL-KTSCG PDVFSGSSYP GVQSYMIVLM
NIIIWLYCTP W-VVLPLTQF W-----DRFV PEGY-LTSCS FDYLS--DNF DTRLFVGTIF
NIIIWLYCTP W-VVLPLTQF W-----DRFV PEGY-LTSCS FDYLS--DNF DTRLFVGTIF
IIFIYMYATP W-VVACYTET W-----GRFV PEGY-LTSCT FDYLT--DNF DTRLFVACIF
IIFIYLYATP W-VVACYTES W-----GRFV PEGY-LTSCT FDYLT--DNF DTRLFVACIF
IIFVWMWSIV W-SVGPVFN- W-----GAYV PEGI-LTSCS FDYLS--TDP STRSFILCMY
IIFVWLWSVL W-AIGPIFG- W-----GAYT LEGV-LCNCS FDYIS--RDS TTRSNILCMF
ALISWVIAIG C-ALPPFFG- W-----GNYI LEGI-LDSCS YDYLT--QDF NTFSYNIFIF
CGLAWVISVG W-SLPPFFG- W-----GSYT LEGI-LDSCS YDYFT--RDM NTITYNICIF
LLFVWIWSGG W-TILPFFG- W-----SRYV PEGN-LTSCT VDYLT--KDW SSASYVVIYG
IIAIWLFSLG W-TIAPMFG- W-----NRYV PEGN-MTACG TDYFN--RGL LSASYLVCYG
IAYIWFMSTI WCCLAPVFG- W-----SRYV PEGN-LTSCG IDYLE--RDW NPRSYLIFYS
---------- --TIPLALG- ------KMYV PEGN-LTSCG IDYLE--RDW NPRSYLIFYS
IAYIWFMSSI W-CLAPAFG- W-----SRYV PEGN-LTSCG IDYLE--RDW NPRSYLIFYS
ILFIWMMAVF W-TVMPLIG- W-----SAYV PEGN-LTACS IDYMT--RMW NPRSYLITYS
IAFIWMMAVF W-TIMPLIG- W-----SSYV PEGN-LTACS IDYMT--RQW NPRSYLITYS

AVAFYIPMSV MLFMYYQIYK AARKSAAK-- ----HKFPGF PRVEPDSV-- ---IALNGIV
AVAFYIPMSV MLFMYYQIYK AARKSAAK-- ----HKFPGF PRVQPESV-- ---ISLNGVV
AVAFYIPMSV MLFMYYQIYK AARKSAAK-- ----HKFPGF PRVQPESV-- ---ISLNGVV
FGAFYIPLLL MLVLYGRIFR AARFRIRKTV KKVEKTGADT RHGASPAPQP KKSVNGESGS
FGAFYIPLLL MLVLYGRIFR AARFRIRKTV RKVEKKGAGT SLGTSSAPPP KKSLNGQPGS
VGAFYLPMLV MMIIYIRIWL VARSRIRK-- ----DKFQMT KARLKTEET- ---TLVASPK
VGAFYLPMLV MMIIYIRIWL VARSRIRK-- ----DKFQMT KARLKTEET- ---TLVASPK
ASSFYVPVLI ILILYWRIYQ TARKRIRR-- ----RRGATA RGGVGPPPVP AGGALVAGGG
IFCFIVPLSL ICFSYTQLLR ALKAVAAQ-- ----QQESAT TQ-------- ----------
CFCFAVPFGT IVFCYGQLLI TLKLAAKA-- ----QADSAS TQ-------- ----------
VIHFIIPVVV IFFSYGRLIC KVREAAAQ-- ----QQESAT TQ-------- ----------
VCHFILPVAV IFFTYGRLVC TVKAAAAQ-- ----QQDSAS TQ-------- ----------
ICHFILPVTI IFFTYGRLVC TVKAAAAQ-- ----QQDSAS TQ-------- ----------
VVHFLVPFVI IFFCYGRLLC TVKEAAAA-- ----QQESAS TQ-------- ----------
VVHFTIPMIV IFFCYGQLVF TVKEAAAQ-- ----QQESAT TQ-------- ----------
VTCFVLPLSL ILFSYTNLLL TLRAAAAQ-- ----QKEADT TQ-------- ----------
ITCCFLPLFI IIVCYLQVWM AIRAVAAQ-- ----QKESES TQ-------- ----------
VTCCFFPLAI IILCYLQVWL AIRAVAAQ-- ----QKESES TQ-------- ----------
VTCCITPLSI IVLCYLQVWL AIRAVAKQ-- ----QKESES TQ-------- ----------
VTCCIIPLAI IMLCYLQVWL AIRAVAKQ-- ----QKESES TQ-------- ----------
FFSFVCPTLM ILYYYSQIVG HVFSHEKA-- ----LREQAK KMNVESLR-- ----------
LFSFVVPTLM ILYYYSQIVG HVFNHEKA-- ----LREQAK KMNVESLR-- ----------
FFSFVCPTTM ITYYYSQIVG HVFSHEKA-- ----LRDQAK KMNVESLR-- ----------
FFSFVCPTTM ITYYYSQIVG HVFSHEKA-- ----LRDQAK KMNVDSLR-- ----------
FCGFMLPIII IAFCYFNIVM SVSNHEKE-- ----MAAMAK RLNAKELR-- ----------
ILGFFGPILI IFFCYFNIVM SVSNHEKE-- ----MAAMAK RLNAKELR-- ----------
VFDYFLPAAI IVFSYVFIVK AIFAHEAA-- ----MRAQAK KMNVSTLR-- ----------
IFDFFLPASV IVFSYVFIVK AIFAHEAA-- ----MRAQAK KMNVTNLR-- ----------
LAVYFLPLIT MIYCYFFIVH AVAEHEKQ-- ----LREQAK KMNVASLR-- ----------
IWVYFVPLFL IIYSYWFIIQ AVAAHEKN-- ----MREQAK KMNVASLR-- ----------
IFVYYIPLFL ICYSYWFIIA AVSAHEKA-- ----MREQAK KMNVKSLR-- ----------
IFVYYIPLFL ICYSYWFIIA AVSAHEKA-- ----MREQAK KMNVKSLR-- ----------
IFVYYIPLFL ICYSYWFIIA AVSAHEKA-- ----MREQAK KMNVKSLR-- ----------
LFVYYTPLFL ICYSYWFIIA AVAAHEKA-- ----MREQAK KMNVKSLR-- ----------
LFVYYTPLFM ICYSYWFIIA TVAAHEKA-- ----MRDQAK KMNVKSLR-- ----------

KLQKEVEECA NLSRLLKH-- ---------- ---------- ---------- ----------
KLQKEVEECA NLSRLLKH-- ---------- ---------- ---------- ----------
KLQKEVEECA NLSRLLKH-- ---------- ---------- ---------- ----------
RNWRLGVESK AGGAL--CAN GAVRQGDDGA ALEVIEVHRV GNSKEHLPLP SEAGPTPCAP
GDWRRCAENR AVGTP--CTN GAVRQGDDEA TLEVIEVHRV GNSKEHLPLP SESGSNSYAP
TEYSVVSDCN GCNSPDSTTE KKKRRAPFKS YGCSPRPERK KNRAKKLP-E NANGVNSNSS
TEYSVVSDCN GCNSPDSTTE KKKRRAPFKS YGCSPRPERK KNRAKKLP-E NANGVNSNSS
SGGIAAAVVA VIGRPLPTIS ETTTTGFTNV SSNNTSPEKQ ---------S CANGLEADPP
---------- ---------- ---------- ---------- ---------- ----------
---------- ---------- ---------- ---------- ---------- ----------
---------- ---------- ---------- ---------- ---------- ----------
---------- ---------- ---------- ---------- ---------- ----------
---------- ---------- ---------- ---------- ---------- ----------
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---------- ---------- ---------- ---------- ---------- ----------

---------- ---------- ---------- ---------- -------ERK NISIFKREQK
---------- ---------- ---------- ---------- -------ERK NISIFKREQK
---------- ---------- ---------- ---------- -------ERK NISIFKREQK
AS-------- ---------- --------FE RK-------- --NERNAEAK RKMALARERK
AC-------- ---------- --------LE RK-------- --NERNAEAK RKMALARERK
SSERLKQIQI ETAEAFANGC AEEASIAMLE RQCNNGKKIS SNDTPYSRTR EKLELKRERK
SSERLKQIQI ETAEAFANGC AEEASIAMLE RQCNNGKKIS SNDTPYSRTR EKLELKRERK
TT-------- ------GYGA VAAAYYPSLV RR-------- -------KPK EAADSKRERK
---------- ---------- ---------- ---------- ---------- -----KAERE
---------- ---------- ---------- ---------- ---------- -----KAERE
---------- ---------- ---------- ---------- ---------- -----KAEKE
---------- ---------- ---------- ---------- ---------- -----KAERE
---------- ---------- ---------- ---------- ---------- -----KAERE
---------- ---------- ---------- ---------- ---------- -----KAEKE
---------- ---------- ---------- ---------- ---------- -----KAEKE
---------- ---------- ---------- ---------- ---------- -----RAERE
---------- ---------- ---------- ---------- ---------- -----KAERE
---------- ---------- ---------- ---------- ---------- -----KAEKE
---------- ---------- ---------- ---------- ---------- -----KAEKE
---------- ---------- ---------- ---------- ---------- -----KAEKE
---------- ---------- ---------- ---------- -------SNV DKSKETAEIR
---------- ---------- ---------- ---------- -------SNV DKSKETAEIR
---------- ---------- ---------- ---------- -------SNV DKNKETAEIR
---------- ---------- ---------- ---------- -------SNV DKSKEAAEIR
---------- ---------- ---------- ---------- ---------K AQAGASAEMK
---------- ---------- ---------- ---------- ---------K AQAGANAEMR
---------- ---------- ---------- ---------- --------SN EADAQRAEIR
---------- ---------- ---------- ---------- --------SN EAETQRAEIR
---------- ---------- ---------- ---------- -------ANA DQQKQSAECR
---------- ---------- ---------- ---------- --------SS ENQNTSAECK
---------- ---------- ---------- ---------- --------SS EDADKSAEGK
---------- ---------- ---------- ---------- --------SS EDAEKSAEGK
---------- ---------- ---------- ---------- --------SS EDAEKSAEGK
---------- ---------- ---------- ---------- --------SS EDCDKSAEGK
---------- ---------- ---------- ---------- --------SS EDCDKSAENK

AATTLGIIVG AFTVCWLPFF LLSTARPFIC GTSCSC-IPL WVERTFLWLG YANSLINPFI
AATTLGIIVG AFTVCWLPFF LLSTARPFIC GTSCSC-IPL WVERTCLWLG YANSLINPFI
AATTLGIIVG AFTVCWLPFF LLSTARPFIC GTSCSC-IPL WVERTCLWLG YANSLINPFI
TVKTLGIIMG TFILCWLPFF IVALVLPF-- -CESSCHMPT LLGAIINWLG YSNSLLNPVI
TVKTLGIIMG TFILCWLPFF IVALVLPF-- -CESSCHMPA LLGAIINWLG YSNSLLNPVI
AARTLAIITG AFLICWLPFF IIALIGPF-- -VDPEG-IPP FARSFVLWLG YFNSLLNPII
AARTLAIITG AFLICWLPFF IIALIGPF-- -VDPEG-IPP FARSFVLWLG YFNSLLNPII
AAKTLAIITG AFVACWLPFF VLAILVPT-- -CDCE--VSP VLTSLSLWLG YFNSTLNPVI
VSRMVVVMVG SFCVCYVPYA AFAMYMVN-- -NRNHG-LDL RLVTIPSFFS KSACIYNPII
VTKMVVVMVL GFLVCWAPYA SFSLWIVS-- -HRGEE-FDL RMATIPSCLS KASTVYNPVI
VTRMVILMVL GFMLAWTPYA VVAFWIFT-- -NKGAD-FTA TLMAVPAFFS KSSSLYNPII
VTKMVILMVF GFLIAWTPYA TVAAWIFF-- -NKGAD-FSA KFMAIPAFFS KSSALYNPVI
VTKMVILMVL GFLVAWTPYA TVAAWIFF-- -NKGAA-FSA QFMAIPAFFS KTSALYNPVI
VTRMVVLMVI GFLVCWVPYA SVAFYIFT-- -HQGSD-FGA TFMTLPAFFA KSSALYNPVI
VTRMVIIMVI FFLICWLPYA SVAMYIFT-- -HQGSN-FGP IFMTLPAFFA KTASIYNPII
VTRMVIVMVM AFLLCWLPYS TFALVVAT-- -HKGII-IQP VLASLPSYFS KTATVYNPII
VSRMVVVMIV AFCICWGPYA SFVSFAAA-- -NPGYA-FHP LAAALPAYFA KSATIYNPVI
VSRMVVVMIV AYCFCWGPYT FFACFAAA-- -NPGYA-FHP LAAALPAYFA KSATIYNPII
VTRMVVVMVL AFCFCWGPYA FFACFAAA-- -NPGYP-FHP LMAALPAFFA KSATIYNPVI
VTRMVVVMIF AYCVCWGPYT FFACFAAA-- -NPGYA-FHP LMAALPAYFA KSATIYNPVI
IAKAAITICF LFFVSWTPYG VMSLIGAF-- -GDKSL-LTQ GATMIPACTC KLVACIDPFV
IAKAAITICF LFFVSWTPYG VMSLIGAF-- -GDKSL-LTP GATMIPACTC KLVACIEPFV
IAKAAITICF LFFCSWTPYG VMSLIGAF-- -GDKTL-LTP GATMIPACAC KMVACIDPFV
IAKAAITICF LFFASWTPYG VMSLIGAF-- -GDKTL-LTP GATMIPACTC KMVACIDPFV
LAKISMVIIT QFMLSWSPYA IIALLAQF-- -GPAEW-VTP YAAELPVLFA KASAIHNPIV
LAKISIVIVS QFLLSWSPYA VVALLAQF-- -GPLEW-VTP YAAQLPVMFA KASAIHNPMI
IAKTALVNVS LWFICWTPYA LISLKGVM-- -GDTSG-ITP LVSTLPALLA KSCSCYNPFV
IAKTALVNVS LWFICWTPYA AITIQGLL-- -GNAEG-ITP LLTTLPALLA KSCSCYNPFV
LAKVAMMTVG LWFMAWTPYL IISWAGVF-- -SSGTR-LTP LATIWGSVFA KANSCYNPIV
LAKVALMTIS LWFMAWTPYL VINFSGIF-- --NLVK-ISP LFTIWGSLFA KANAVYNPIV
LAKVALVTIS LWFMAWTPYL VINCMGLF-- --KFEG-LTP LNTIWGACFA KSAACYNPIV
LAKVALVTIT LWFMAWTPYL VINCMGLF-- --KFEG-LTP LNTIWGACFA KSAACYNPIV
LAKVALVTIT LWFMAWTPYL VINCMGLF-- --KFEG-LTP LNTIWGACFA KSAACYNPIV
LAKVALTTIS LWFMAWTPYL VICYFGLF-- --KIDG-LTP LTTIWGATFA KTSAVYNPIV
LAKVALTTIS LWFMAWTPYL IICYFGLF-- --KIDG-LTP LTTIWGATFA KTSAVYNPIV

YAFFNRDLRT TYRSLLQC-Q YRNINRKLSA AGMHEALKLA ERPER----- ----------
YAFFNRDLRP TSRSLLQC-Q YRNINRKLSA AGMHEALKLA ERPER----- ----------
YAFFNRDLRT TYRSLLQC-Q YRNINRKLSA AGMHEALKLA ERPER----- ----------
YAYFNKDFQN AFKKIIKC-K FCRQ------ ---------- ---------- ----------
YAYFNKDFQN AFKKIIKC-K FCRR------ ---------- ---------- ----------
YTIFSPEFRS AFQKILFG-K YRRGHR---- ---------- ---------- ----------
YTIFSPEFRS AFQKILFG-K YRRGHR---- ---------- ---------- ----------
YTVFSPEFRH AFQRLLCG-R RVRRRRAPQ- ---------- ---------- ----------
YCFMNKQFQA CIMKMVCG-K AMTDESDTCS SQKTEVSTVS STQ------- ----------
YVLMNKQFRS CMMKMVCG-K NIEEDEASTS SQVTQVSSVA PEK------- ----------
YVLMNKQFRN CMITTICC-G KNPFGDEDVS STVSQSKTEV SSV------- ----------
YVLLNKQFRN CMLTTIFC-G KNPLGDDESS TVSTSKTEVS S--------- ----------
YVLLNKQFRS CMLTTLFC-G KNPLGDEESS TVSTSKTEVS S--------- ----------
YILMNKQFRN CMITTLCC-G KNPLGDDESG ASTSKTEVSS VST------- ----------
YIMMNKQFRN CMLTSLCC-G KNPLGDDEAS ATASKTETSQ ---------- ----------
YVFMNKQFQS CLLEMLCC-G YQPQRTGKAS PGTPGPHADV TAA------- ----------
YVFMNRQFRN CIMQLFG--K KVDDGSEAST TSRTEVSSVS NSS------- ----------
YVFMNRQFRN CILQLF---G KKVDDGSEVS TSRTEVSSVS NSS------- ----------
YVFMNRQFRN CILQLFG--K KVDDGSELSS ASKTEVSSVS S--------- ----------
YVFMNRQFRN CILQLF---- --GKKVDDGS ELSSASKTEV SSV------- ----------
YAISHPRYRL ELQKRCPWLG VNEKSGEISS AQSTTTQEQ- QQT------- ----------
YAISHPRYRM ELQKRCPWLG VNEKSGEASS AQSTTTQEQT QQT------- ----------
YAISHPRYRM ELQKRCPW-L ALNEKAPESS AVASTSTTQE PQQ------- ----------
YAISHPRYRM ELQKRCPW-L AISEKAPESR AAISTSTTQE QQQ------- ----------
YSVSHPKFRE AIQTTFPWLL TCCQFDEKEC EDANDAEEEV VASER--GGE SRDAAQMKEM
YSVSHPKFRE AISQTFPWVL TCCQFDDKET EDDKDAETEI PAGESSDAAP SADAAQMKEM
YAISHPKYRL AITQHLPWFC VHETETKSND DSQSNSTVAQ DKA------- ----------
YAISHPKFRL AITQHLPWFC VHEKDPNDVE ENQSSNTQTQ EKS------- ----------
YGISHPRYKA ALYQRFPS-L ACGSGESGSD VKSEASATTT MEE------- ----------
YGISHPKYRA ALFAKFPS-L ACAAEPSSDA VSTTSGTTTV TDN------- ----------
YGISHPKYRL ALKEKCPC-C VFGKVDDGKS SEAQSQATTS EAE------- ----------
YGISHPKYRL ALKEKCPC-C VFGKVDDGKS SDAQSQATAS EAE------- ----------
YGISHPKYRL ALKEKCPC-C VFGKVDDGKS SDAQSQATAS EAE------- ----------
YGISHPKYRI VLKEKCPM-C VFGNTDEPKP DAPASDTETT SEA------- ----------
YGISHPNDRL VLKEKCPM-C VCGTTDEPKP DAPPSDTETT SEA------- ----------

---------- -----PEFVL QNADYCRKKG HDS------- ---------- ----------
---------- -----SEFVL QNSDHCGKKG HDT------- ---------- ----------
---------- -----SEFVL QNSDHCGKKG HDT------- ---------- ----------
---------- ---------- ---------- ---------- ---------- ----------
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---------- ---------- ---------- ---------- ---------- ----------
---------- ---------- ---------V GPN------- ---------- ----------
---------- ---------- ---------- ---------- ---------- ----------
---------- ---------- -----SSSQV SPA------- ---------- ----------
---------- ---------- ---------V SPA------- ---------- ----------
---------- ---------- ---------V SPA------- ---------- ----------
---------- ---------- -------SPV SPA------- ---------- ----------
---------- ---------- ---------V APA------- ---------- ----------
---------- ---------- ----GLRNKV MPAHPV---- ---------- ----------
---------- ---------- ---------V APA------- ---------- ----------
---------- ---------- ---------V SPA------- ---------- ----------
---------- ---------- ---------V SPA------- ---------- ----------
---------- ---------- -------SSV SPA------- ---------- ----------
---------- ---------- ---------- TAA------- ---------- ----------
---------- ---------- ---------- SAA------- ---------- ----------
---------- ---------- ---------T TAA------- ---------- ----------
---------- ---------- ---------T TAA------- ---------- ----------
MAMMQKMQAQ QAAYQP---P PPPQGYPPQG YPPQGAYPPP QGYPPQGYPP QGYPPQGYPP
MAMMQKMQQQ QAAYPPQGYA PPPQGYPPQG YPPQGY--PP QGYPPQGYPP ---PPQGAPP
---------- ---------- ---------- ---------- ---------- ----------
---------- ---------- ---------- ---------- ---------- ----------
---------- ---------- ------KPKI PEA------- ---------- ----------
---------- ---------- --------EK SNA------- ---------- ----------
---------- ---------- ---------- SKA------- ---------- ----------
---------- ---------- ---------- SKA------- ---------- ----------
---------- ---------- ---------- SKA------- ---------- ----------
---------- ---------- ---------D SKA------- ---------- ----------
---------- ---------- ---------E SKD------- ---------- ----------

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QGAPPQVEAP QGAPPQGVDN QAYQA
QGAPP----- -AAPPQGVDN QAYQA
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