>M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
MN-----------------GTE--GDNFYVP----FS---------------------NK
TGLARSPY----------------------EYPQY-YLAEPWK---------YSALAAYM
FFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTSMN-GY
FV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-FRFGNTHAIMGVAF
TWIMALAC-AAPPLVG-W-----SRYIPEGMQCSCGPDYYTLNPNFNNESYVVYMFVVHF
LVPFVIIFFCYGRLLCTV------------------------------------------
------------------------------------------------------------
---------------------KEAAAAQQ----------ESASTQKA-------------
----------------EKEVTRMVVLMVIGFLVCWVPYASVAFYIFTHQGSD---FGATF
MTLPAFFAKSSALYNPVIYILMNKQFRNCMITT----LCCGKNPLGDDE--SGASTSKTE
VSS---------------------------------------------------------
--------------------------------VS-TSPVSP-A---
>U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
MN-----------------GTE--GPNFYVP----FS---------------------NI
TGVVRSPF----------------------EQPQY-YLAEPWQ---------FSMLAAYM
FLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLH-GY
FV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-FRFGENHAIMGVAF
TWVMALAC-AAPPLVG-W-----SRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHF
TIPMIVIFFCYGQLVFTV------------------------------------------
------------------------------------------------------------
---------------------KEAAAQQQ----------ESATTQKA-------------
----------------EKEVTRMVIIMVIFFLICWLPYASVAMYIFTHQGSN---FGPIF
MTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTS----LCCGKNPLGDDE--ASATASKTE
------------------------------------------------------------
-----------------------------------TSQVAP-A---
>M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
MN-----------------GTE--GINFYVP----MS---------------------NK
TGVVRSPF----------------------EYPQY-YLAEPWK---------YRLVCCYI
FFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYTAWN-GY
FV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-FRFSATHAMMGIAF
TWVMAFSC-AAPPLFG-W-----SRYMPEGMQCSCGPDYYTHNPDYHNESYVLYMFVIHF
IIPVVVIFFSYGRLICKV------------------------------------------
------------------------------------------------------------
---------------------REAAAQQQ----------ESATTQKA-------------
----------------EKEVTRMVILMVLGFMLAWTPYAVVAFWIFTNKGAD---FTATL
MAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITT----ICCGKNPFGDEDVSSTVSQSKTE
VSS---------------------------------------------------------
--------------------------------VS-SSQVSP-A---
>A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
MN-----------------GTE--GKNFYVP----MS---------------------NR
TGLVRSPF----------------------EYPQY-YLAEPWQ---------FKILALYL
FFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTAIN-GY
FV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSSHAFAGIAF
TWVMALAC-AAPPLFG-W-----SRYIPEGMQCSCGPDYYTLNPDYNNESYVIYMFVCHF
ILPVAVIFFTYGRLVCTV------------------------------------------
------------------------------------------------------------
---------------------KAAAAQQQ----------DSASTQKA-------------
----------------EREVTKMVILMVFGFLIAWTPYATVAAWIFFNKGAD---FSAKF
MAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTT----IFCGKNPLGDDE-SSTVSTSKTE
VSS---------------------------------------------------------
--------------------------------------VSP-A---
>B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
MN-----------------GTE--GNNFYVP----LS---------------------NR
TGLVRSPF----------------------EYPQY-YLAEPWQ---------FKLLAVYM
FFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTAIN-GY
FA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSTHASAGIAF
TWVMAMAC-AAPPLVG-W-----SRYIPEGIQCSCGPDYYTLNPEYNNESYVLYMFICHF
ILPVTIIFFTYGRLVCTV------------------------------------------
------------------------------------------------------------
---------------------KAAAAQQQ----------DSASTQKA-------------
----------------EREVTKMVILMVLGFLVAWTPYATVAAWIFFNKGAA---FSAQF
MAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTT----LFCGKNPLGDEE-SSTVSTSKTE
VSS---------------------------------------------------------
--------------------------------------VSP-A---
>L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
MK-----------------QVPEFHEDFYIPIPLDIN---------------------NL
S--AYSPF----------------------LVPQD-HLGNQGI---------FMAMSVFM
FFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSFFN-RY
FI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-FTFKTPHAIAGCIL
PWISALAA-SLPPLFG-W-----SRYIPEGLQCSCGPDWYTTNNKYNNESYVMFLFCFCF
AVPFGTIVFCYGQLLITL------------------------------------------
------------------------------------------------------------
---------------------KLAAKAQA----------DSASTQKA-------------
----------------EREVTKMVVVMVLGFLVCWAPYASFSLWIVSHRGEE---FDLRM
ATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-K----MVCGKN-IEEDE--ASTSSQVTQ
VSS---------------------------------------------------------
--------------------------------------VAPEK---
>M13299   1 human BCP <>[Science232(4747),193-202'86]
MR-----------------KMS--EEEFYL-----FK---------------------NI
SSV--GPW----------------------DGPQY-HIAPVWA---------FYLQAAFM
GTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVASCN-GY
FV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-FRFSSKHALTVVLA
TWTIGIGV-SIPPFFG-W-----SRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCF
IVPLSLICFSYTQLLRAL------------------------------------------
------------------------------------------------------------
---------------------KAVAAQQQ----------ESATTQKA-------------
----------------EREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHG---LDLRL
VTIPSFFSKSACIYNPIIYCFMNKQFQACIM-K----MVCGKA-MTDES--DTCSSQKTE
VST---------------------------------------------------------
--------------------------------VS-STQVGP-N---
>K03494   1 human GCP <>[Science232(4747),193-202'86]
MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYT----NS---------------------NS
T---RGPF----------------------EGPNY-HIAPRWV---------YHLTSVWM
IFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVNQVY-GY
FV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-VRFDAKLAIVGIAF
SWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCC
ITPLSIIVLCYLQVWLAI------------------------------------------
------------------------------------------------------------
---------------------RAVAKQQK----------ESESTQKA-------------
----------------EKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYP---FHPLM
AALPAFFAKSATIYNPVIYVFMNRQFRNCILQL----F-----GKKVDDGSELSSASKTE
VSS---------------------------------------------------------
--------------------------------V---SSVSP-A---
>Z68193   1 human Red Opsin <>[]
MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYT----NS---------------------NS
T---RGPF----------------------EGPNY-HIAPRWV---------YHLTSVWM
IFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVNQVS-GY
FV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGIAF
SWIWSAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCC
IIPLAIIMLCYLQVWLAI------------------------------------------
------------------------------------------------------------
---------------------RAVAKQQK----------ESESTQKA-------------
----------------EKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYA---FHPLM
AALPAYFAKSATIYNPVIYVFMNRQFRNCILQL----F-----GKKVDDGSELSSASKTE
VSS---------------------------------------------------------
--------------------------------V---SSVSP-A---
>M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
MTEAWNVAVFAARRSRDD-DDTTRGSVFTYT----NT---------------------NN
T---RGPF----------------------EGPNY-HIAPRWV---------YNLVSFFM
IIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFNQIF-GY
FI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-IKFDSKLAIIGIVF
SWVWAWGW-SAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSVELGCQSFMLTLMITCC
FLPLFIIIVCYLQVWMAI------------------------------------------
------------------------------------------------------------
---------------------RAVAAQQK----------ESESTQKA-------------
----------------EREVSRMVVVMIVAFCICWGPYASFVSFAAANPGYA---FHPLA
AALPAYFAKSATIYNPVIYVFMNRQFRNCIMQL----F-----GKKVDDGSEASTTSRTE
VSS---------------------------------------------------------
--------------------------------VS-NSSVAP-A---
>M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
MA-AWEAAFAARRRHEE--EDTTRDSVFTYT----NS---------------------NN
T---RGPF----------------------EGPNY-HIAPRWV---------YNLTSVWM
IFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVINQIS-GY
FI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-IKFDGKLAVAGILF
SWLWSCAW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSDPGVQSYMVVLMVTCC
FFPLAIIILCYLQVWLAI------------------------------------------
------------------------------------------------------------
---------------------RAVAAQQK----------ESESTQKA-------------
----------------EKEVSRMVVVMIVAYCFCWGPYTFFACFAAANPGYA---FHPLA
AALPAYFAKSATIYNPIIYVFMNRQFRNCILQL----F-----GKKVDDGSEVST-SRTE
VSS---------------------------------------------------------
--------------------------------VS-NSSVSP-A---
>S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
MS-----------------SNSSQAP----------P---------------------NG
T---PGPF----------------------DGPQWPYQAPQST---------YVGVAVLM
GTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNNIN-GF
FV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-FQFQRRHAVSGCAF
TWGWALLW-SAPPLLG-W-----SSYVPEGLRTSCGPNWYTGGSNN--NSYILSLFVTCF
VLPLSLILFSYTNLLLTL------------------------------------------
------------------------------------------------------------
---------------------RAAAAQQK----------EADTTQRA-------------
----------------EREVTRMVIVMVMAFLLCWLPYSTFALVVATHKGII---IQPVL
ASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEM----LCCGYQPQRTGKASPGTPGPHAD
VTA---------------------------------------------------------
--------------------------------AGLRNKVMP-AHPV
>M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
MESGNVSSSLFGNVSTALRPEA----RLSA---E------------------------TR
LLGWNVPP----------------------EELR--HIPEHWLTYPEPPESMNYLLGTLY
IFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFIYNSFH-QG
YA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMIIF
IYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDYLT--DNFDTRLFVACIFFFSF
VCPTTMITYYYSQIVGHVFSH---------------------------------------
------------------------------------------------------------
--------------------EKALRDQAKKMNVESLRSNVDKNKETA-------------
----------------EIRIAKAAITICFLFFCSWTPYGVMSLIGAFGDKTL---LTPGA
TMIPACACKMVACIDPFVYAISHPRYRMELQKRCPW-LALNEKAPES----SAVASTSTT
QEP---------------------------------------------------------
------------------------------------QQTTA-A---
>X65879   1 Drosophila pseudoobscura Rh3 <>[Genetics132(1),193-204'92
MEYHNVSSVL-GNVSSVLRPDA----RLSA---E------------------------SR
LLGWNVPP----------------------DELR--HIPEHWLIYPEPPESMNYLLGTLY
IFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFIYNSFH-QG
YA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMIIF
IYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDYLT--DNFDTRLFVACIFFFSF
VCPTTMITYYYSQIVGHVFSH---------------------------------------
------------------------------------------------------------
--------------------EKALRDQAKKMNVDSLRSNVDKSKEAA-------------
----------------EIRIAKAAITICFLFFASWTPYGVMSLIGAFGDKTL---LTPGA
TMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPW-LAISEKAPES----RAAISTSTT
QEQ---------------------------------------------------------
------------------------------------QQTTA-A---
>M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
ME------PLCNASEPPLRPEA----R-SSGNGD------------------------LQ
FLGWNVPP----------------------DQIQ--YIPEHWLTQLEPPASMHYMLGVFY
IFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF--NSFH-RG
FAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNII
IWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLFVGTIFFFSF
VCPTLMILYYYSQIVGHVFSH---------------------------------------
------------------------------------------------------------
--------------------EKALREQAKKMNVESLRSNVDKSKETA-------------
----------------EIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSL---LTQGA
TMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPW-LGVNEKSGEI----SSAQSTTTQ
EQ----------------------------------------------------------
------------------------------------QQTTA-A---
>X65880   1 Drosophila pseudoobscura Rh4 <>[Genetics132(1),193-204'92
MD------ALCNASEPPLRPEA----RMSSGSDE------------------------LQ
FLGWNVPP----------------------DQIQ--YIPEHWLTQLEPPASMHYMLGVFY
IFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFIYNSFH-RG
FA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMNII
IWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DNFDTRLFVGTIFLFSF
VVPTLMILYYYSQIVGHVFNH---------------------------------------
------------------------------------------------------------
--------------------EKALREQAKKMNVESLRSNVDKSKETA-------------
----------------EIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSL---LTPGA
TMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPW-LGVNEKSGEA----SSAQSTTTQ
EQT---------------------------------------------------------
------------------------------------QQTSA-A---
>D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
MT-----------NATGPQMAYYGAASMDFGYPE------------------------GV
SIVDFVRP----------------------EIKP--YVHQHWYNYPPVNPMWHYLLGVIY
LFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYNCFSGGV
WM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-PKLTTGKAVVFALI
SWVIAIGC-ALPPFFG-W-----GNYILEGILDSCSYDYLT--QDFNTFSYNIFIFVFDY
FLPAAIIVFSYVFIVKAIFAH---------------------------------------
------------------------------------------------------------
--------------------EAAMRAQAKKMNVSTLRS-NEADAQRA-------------
----------------EIRIAKTALVNVSLWFICWTPYALISLKGVMGDTSG---ITPLV
STLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPW-FCVHETETKS-NDDSQSNSTVAQ
------------------------------------------------------------
---------------------------------------DK-A---
>D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
MA-----------NVTGPQMAFYGSGAATFGYPE------------------------GM
TVADFVPD----------------------RVKH--MVLDHWYNYPPVNPMWHYLLGVVY
LFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYNCFSGGR
WM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-PKLTQGKATFMCGL
AWVISVGW-SLPPFFG-W-----GSYTLEGILDSCSYDYFT--RDMNTITYNICIFIFDF
FLPASVIVFSYVFIVKAIFAH---------------------------------------
------------------------------------------------------------
--------------------EAAMRAQAKKMNVTNLRS-NEAETQRA-------------
----------------EIRIAKTALVNVSLWFICWTPYAAITIQGLLGNAEG---ITPLL
TTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPW-FCVHEKDPND-VEENQSSNTQTQ
------------------------------------------------------------
---------------------------------------EK-S---
>K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
ME-----SFAVAAAQLGPHFA-----PLS-----------------------------NG
SVVDKVTP----------------------DMAH--LISPYWNQFPAMDPIWAKILTAYM
IMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ET
WV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKM--
-------------------------YVPEGNLTSCGIDYLE--RDWNPRSYLIFYSIFVY
YIPLFLICYSYWFIIAAVSAH---------------------------------------
------------------------------------------------------------
--------------------EKAMREQAKKMNVKSLRS-SEDAEKSA-------------
----------------EGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-EG---LTPLN
TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPC-CVFGKVDDGK-SSDAQSQATASE
AE----------------------------------------------------------
---------------------------------------SK-A---
>K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
ME-----SFAVAAAQLGPHFA-----PLS-----------------------------NG
SVVDKVTP----------------------DMAH--LISPYWNQFPAMDPIWAKILTAYM
IMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ET
WV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKIAY
IWFMSSIW-CLAPAFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSYLIFYSIFVY
YIPLFLICYSYWFIIAAVSAH---------------------------------------
------------------------------------------------------------
--------------------EKAMREQAKKMNVKSLRS-SEDAEKSA-------------
----------------EGKLAKVALVTITLWFMAWTPYLVINCMGLFKF-EG---LTPLN
TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPC-CVFGKVDDGK-SSDAQSQATASE
AE----------------------------------------------------------
---------------------------------------SK-A---
>X65877   1 Drosophila pseudoobscura ninaE <>[Genetics132(1),193-204'
MD-----SFAAVATQLGPQFA-----APS-----------------------------NG
SVVDKVTP----------------------DMAH--LISPYWDQFPAMDPIWAKILTAYM
IIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINLYF-ET
WV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKIAY
IWFMSTIWCCLAPVFG-W-----SRYVPEGNLTSCGIDYLE--RDWNPRSYLIFYSIFVY
YIPLFLICYSYWFIIAAVSAH---------------------------------------
------------------------------------------------------------
--------------------EKAMREQAKKMNVKSLRS-SEDADKSA-------------
----------------EGKLAKVALVTISLWFMAWTPYLVINCMGLFKF-EG---LTPLN
TIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPC-CVFGKVDDGK-SSEAQSQATTSE
AE----------------------------------------------------------
---------------------------------------SK-A---
>M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
MERSHLPETPFDLAHSGPRFQ-----AQSSG---------------------------NG
SVLDNVLP----------------------DMAH--LVNPYWSRFAPMDPMMSKILGLFT
LAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ET
WV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKILF
IWMMAVFW-TVMPLIG-W-----SAYVPEGNLTACSIDYMT--RMWNPRSYLITYSLFVY
YTPLFLICYSYWFIIAAVAAH---------------------------------------
------------------------------------------------------------
--------------------EKAMREQAKKMNVKSLRS-SEDCDKSA-------------
----------------EGKLAKVALTTISLWFMAWTPYLVICYFGLFKI-DG---LTPLT
TIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPM-CVFGNTDEPKPDAPASDTETTSE
AD----------------------------------------------------------
---------------------------------------SK-A---
>X65878   1 Drosophila pseudoobscura Rh2 <>[Genetics132(1),193-204'92
MERSLLPEPPLAMALLGPRFE-----AQTGG---------------------------NR
SVLDNVLP----------------------DMAP--LVNPHWSRFAPMDPTMSKILGLFT
LVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINFYY-ET
WV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKIAF
IWMMAVFW-TIMPLIG-W-----SSYVPEGNLTACSIDYMT--RQWNPRSYLITYSLFVY
YTPLFMICYSYWFIIATVAAH---------------------------------------
------------------------------------------------------------
--------------------EKAMRDQAKKMNVKSLRS-SEDCDKSA-------------
----------------ENKLAKVALTTISLWFMAWTPYLIICYFGLFKI-DG---LTPLT
TIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPM-CVCGTTDEPKPDAPPSDTETTSE
AE----------------------------------------------------------
---------------------------------------SK-D---
>U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
MI-----------AVSGPSYE-----AFSYGGQARFN---------------------NQ
TVVDKVPP----------------------DMLH--LIDANWYQYPPLNPMWHGILGFVI
GMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVINCYY-ET
WV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-KPLSINGALIRIIA
IWLFSLGW-TIAPMFG-W-----NRYVPEGNMTACGTDYFN--RGLLSASYLVCYGIWVY
FVPLFLIIYSYWFIIQAVAAH---------------------------------------
------------------------------------------------------------
--------------------EKNMREQAKKMNVASLRS-SENQNTSA-------------
----------------ECKLAKVALMTISLWFMAWTPYLVINFSGIFNL-VK---ISPLF
TIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPS-LAC-AAEPSS-DAVSTTSGTTTV
TDN---------------------------------------------------------
------------------------------------EK-SN-A---
>L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
M-------------ANQLSYS-----SLGWPYQP------------------------NA
SVVDTMPK----------------------EMLY--MIHEHWYAFPPMNPLWYSILGVAM
IILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNCFA-ET
WI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-APLTHKKATLLLLF
VWIWSGGW-TILPFFG-W-----SRYVPEGNLTSCTVDYLT--KDWSSASYVVIYGLAVY
FLPLITMIYCYFFIVHAVAEH---------------------------------------
------------------------------------------------------------
--------------------EKQLREQAKKMNVASLRANADQQKQSA-------------
----------------ECRLAKVAMMTVGLWFMAWTPYLIISWAGVFSSGTR---LTPLA
TIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPS-LACGSGESGS-DVKSEASATTTM
EEK---------------------------------------------------------
------------------------------------PKIPE-A---
>X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
MVE-----------------------STTLVNQTWWY---------------------NP
TVD----------------------------------IHPHWAKFDPIPDAVYYSVGIFI
GVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISAFM-KK
WI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMIIF
VWMWSIVW-SVGPVFN-W-----GAYVPEGILTSCSFDYLS--TDPSTRSFILCMYFCGF
MLPIIIIAFCYFNIVMSVSNH---------------------------------------
------------------------------------------------------------
--------------------EKEMAAMAKRLNAKELR--KAQAGASA-------------
----------------EMKLAKISMVIITQFMLSWSPYAIIALLAQFGPAEW---VTPYA
AELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKECEDANDAEEEVVA
SER--GGESRDAAQMKEMMAMMQKMQAQQAAYQPPPPPQGY--PPQGYPPQGAYPPPQGY
PPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQ-A---
>X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
MGR-----------------------DLR-DNETWWY---------------------NP
SIV----------------------------------VHPHWREFDQVPDAVYYSLGIFI
GICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFL-KK
WI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIF
VWLWSVLW-AIGPIFG-W-----GAYTLEGVLCNCSFDYIS--RDSTTRSNILCMFILGF
FGPILIIFFCYFNIVMSVSNH---------------------------------------
------------------------------------------------------------
--------------------EKEMAAMAKRLNAKELR--KAQAGANA-------------
----------------EMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEW---VTPYA
AQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAETEIPA
GESSDAAPSADAAQMKEMMAMMQKMQQQQAAY----PPQGYAPPPQGYPPQGY--PPQGY
PPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQAYQ-A---
>L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
MMDVNSSGRPDLYGHLRSFL-----LPEVGRGLPDLSPDGGADPVAGSWAPHLLS---EV
TASPAPTW------------DAPPDNASGCGEQIN------------YGRVEKVVIGSIL
TLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGK
WI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILS
VWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIYSTAVAF
YIPMSVMLFMYYQIYKAAR-----------------------------------------
---------KSAAKHKFPGFPRVEPDSVIAL-----------------------------
--------------------NGIVKLQKEVEECANLSRLL--------------------
----KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
ERTFLWLGYANSLINPFIYAFFNRDLRTTYRSL----L---QCQYRNINRKLSAAGMHEA
LKLAERPERPEFVLQNADYCRKK-------------------------------------
------------------------------------------GHDS
>L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
M-------------------------------------------------PHLLSGFLEV
TASPAPTW------------DAPPDNVSGCGEQIN------------YGRVEKVVIGSIL
TLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGK
WI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILS
VWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIYSTAVAF
YIPMSVMLFMYYQIYKAAR-----------------------------------------
---------KSAAKHKFPGFPRVQPESVISL-----------------------------
--------------------NGVVKLQKEVEECANLSRLL--------------------
----KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
ERTCLWLGYANSLINPFIYAFFNRDLRPTSRSL----L---QCQYRNINRKLSAAGMHEA
LKLAERPERSEFVLQNSDHCGKK-------------------------------------
------------------------------------------GHDT
>A47425 serotonin receptor 5HT-7 - rat
M-------------------------------------------------PHLLSGFLEV
TASPAPTW------------DAPPDNVSGCGEQIN------------YGRVEKVVIGSIL
TLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIGGK
WI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILS
VWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF----------GYTIYSTAVAF
YIPMSVMLFMYYQIYKAAR-----------------------------------------
---------KSAAKHKFPGFPRVQPESVISL-----------------------------
--------------------NGVVKLQKEVEECANLSRLL--------------------
----KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV
ERTCLWLGYANSLINPFIYAFFNRDLRTTYRSL----L---QCQYRNINRKLSAAGMHEA
LKLAERPERSEFVLQNSDHCGKK-------------------------------------
------------------------------------------GHDT
>M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
MDVLSPGQ-----------------GNNTTSPPAPFETGG------------------NT
TGISDVTV------------------------------------------SYQVITSLLL
GTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NK
WT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISL
TWLIGFLI-SIPPMLG-WRTPEDRSDPDA---CTISKDH----------GYTIYSTFGAF
YIPLLLMLVLYGRIFRAARFRIRK------------------------------------
---TVKKVEKTGADTRHGASPAPQPKKS-----------VNGESGSR---------NWRL
GVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAG--PTPCAPASFER
KNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSCH-MPTLL
GAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKI----I-----KCKFCRQ----------
------------------------------------------------------------
----------------------------------------------
>A35181 serotonin receptor class 1A - rat
MDVFSFGQ-----------------GNNTTASQEPFGTGG------------------NV
TSISDVTF------------------------------------------SYQVITSLLL
GTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQVL-NK
WT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISL
TWLIGFLI-SIPPMLG-WRTPEDRSDPDA---CTISKDH----------GYTIYSTFGAF
YIPLLLMLVLYGRIFRAARFRIRK------------------------------------
---TVRKVEKKGAGTSLGTSSAPPPKKS-----------LNGQPGSG---------DWRR
CAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESG--SNSYAPACLER
KNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSCH-MPALL
GAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKI----I-----KCKFCRR----------
------------------------------------------------------------
----------------------------------------------
>L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTG------------------LV
TSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNMTDDRYWSLTVYSHEHLVLTSVIL
GLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KV
WF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMV
VWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYTIFSTVGAF
YLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNS
PDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS----------SERL
KQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS-------------
RTREKLELK------RERKAARTLAIITGAFLICWLPFFIIALIGPF-VDPE-G-IPPFA
RSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKI----LFG---KYRRGHR----------
------------------------------------------------------------
----------------------------------------------
>A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTG------------------LV
TSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNMTDDRYWSLTVYSHEHLVLTSVIL
GLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSEIS-KV
WF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMIMV
VWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK----------GYTIFSTVGAF
YLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNS
PDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSS----------SERL
KQIQIETAEAFANGCA----EEASIAMLERQ-CNNGKKISSNDTPYS-------------
RTREKLELK------RERKAARTLAIITGAFLICWLPFFIIALIGPF-VDPE-G-IPPFA
RSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKI----LFG---KYRRGHR----------
------------------------------------------------------------
----------------------------------------------
>X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
MEGAE-GQEELDWEAL--YLRLP--LQNCSWNSTGWEPNW------------------NV
TVVPNTTW---------WQASAPFDTPAALVRAAAK--------------------AVVL
GLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVYEVV-QR
WT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGMMIAC
VWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV----------GYQIFATASSF
YVPVLIILILYWRIYQTARKRIR-------------------------------------
--------RRRGATARGGVGPPP---------VPAGGALVAGGGSGGIAAAVVAVIGRPL
PTISETTTTGFTNVSS----NNTS---PEKQSCANGLEADPPTTGYGAVAAAYYPSLVRR
KPKEAADSK------RERKAAKTLAIITGAFVACWLPFFVLAILVPT-CDCE---VSPVL
TSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRL----LCGRRVRRRRAPQ----------
------------------------------------------------------------
----------------------------------------------
