>M63632    1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
MNGTEGD---------------------------NFYVP-------F-------------
-----------SN-KTG-----------------LA--RSPYEYPQYY-LAEPWKYSALA
AYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLF-GFTVTM-YTSM
N-GYFVFGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-FRFGNTHAIMGV
AFTWIMALAC-AAPPL-VGWSR-----YIPEGMQ---CSCGPDYYTLNPNFNNESYVVYM
FVVHFLVPFVIIFFCYGRLLCTVKEAAAAQ------------------------------
------------------------------------------------------------
-----------Q------------------------------------------------
-----------------ES-ASTQKAEKEVTRMVVLMVIGFLVCWVPYASVAFYIFTHQG
SD--FGAT-FMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLC----C-GKNPLGDDE
-SG-AS-TSKTEVS-------------S--------------------------------
----------------------------------------------------------VS
TSPVSPA
>U22180    1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
MNGTEGP---------------------------NFYVP-------F-------------
-----------SN-ITG-----------------VV--RSPFEQPQYY-LAEPWQFSMLA
AYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFG-GFTTTL-YTSL
H-GYFVFGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-FRFGENHAIMGV
AFTWVMALAC-AAPPL-VGWSR-----YIPEGMQ---CSCGIDYYTLKPEVNNESFVIYM
FVVHFTIPMIVIFFCYGQLVFTVKEAAAQQ------------------------------
------------------------------------------------------------
-----------Q------------------------------------------------
-----------------ES-ATTQKAEKEVTRMVIIMVIFFLICWLPYASVAMYIFTHQG
SN--FGPI-FMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLC----C-GKNPLGDDE
-AS-AT-ASKTE------------------------------------------------
------------------------------------------------------------
TSQVAPA
>M92038    1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
MNGTEGI---------------------------NFYVP-------M-------------
-----------SN-KTG-----------------VV--RSPFEYPQYY-LAEPWKYRLVC
CYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACF-GFTVTF-YTAW
N-GYFVFGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-FRFSATHAMMGI
AFTWVMAFSC-AAPPL-FGWSR-----YMPEGMQ---CSCGPDYYTHNPDYHNESYVLYM
FVIHFIIPVVVIFFSYGRLICKVREAAAQQ------------------------------
------------------------------------------------------------
-----------Q------------------------------------------------
-----------------ES-ATTQKAEKEVTRMVILMVLGFMLAWTPYAVVAFWIFTNKG
AD--FTAT-LMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTIC----C-GKNPFGDED
VSSTVS-QSKTEVS-------------S--------------------------------
----------------------------------------------------------VS
SSQVSPA
>A45229  opsin, green-sensitive (clone GFgr-1) - goldfish
MNGTEGK---------------------------NFYVP-------M-------------
-----------SN-RTG-----------------LV--RSPFEYPQYY-LAEPWQFKILA
LYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCF-GFTVTF-YTAI
N-GYFVLGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSSHAFAGI
AFTWVMALAC-AAPPL-FGWSR-----YIPEGMQ---CSCGPDYYTLNPDYNNESYVIYM
FVCHFILPVAVIFFTYGRLVCTVKAAAAQQ------------------------------
------------------------------------------------------------
-----------Q------------------------------------------------
-----------------DS-ASTQKAEREVTKMVILMVFGFLIAWTPYATVAAWIFFNKG
AD--FSAK-FMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIF----C-GKNPLGDDE
-SSTVS-TSKTE------------------------------------------------
------------------------------------------------------------
VSSVSPA
>B45229  opsin, green-sensitive (clone GFgr-2) - goldfish
MNGTEGN---------------------------NFYVP-------L-------------
-----------SN-RTG-----------------LV--RSPFEYPQYY-LAEPWQFKLLA
VYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCF-GFTVTF-YTAI
N-GYFALGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSTHASAGI
AFTWVMAMAC-AAPPL-VGWSR-----YIPEGIQ---CSCGPDYYTLNPEYNNESYVLYM
FICHFILPVTIIFFTYGRLVCTVKAAAAQQ------------------------------
------------------------------------------------------------
-----------Q------------------------------------------------
-----------------DS-ASTQKAEREVTKMVILMVLGFLVAWTPYATVAAWIFFNKG
AA--FSAQ-FMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLF----C-GKNPLGDEE
-SSTVS-TSKTE------------------------------------------------
------------------------------------------------------------
VSSVSPA
>L11864    1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
MKQVPEFH-E------------------------DFYIP-------I-------------
-------P--LDI-NNL-----------------SA--YSPFLVPQDH-LGNQGIFMAMS
VFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIF-GSPLSF-YSFF
N-RYFIFGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-FTFKTPHAIAGC
ILPWISALAA-SLPPL-FGWSR-----YIPEGLQ---CSCGPDWYTTNNKYNNESYVMFL
FCFCFAVPFGTIVFCYGQLLITLKLAAKAQ------------------------------
------------------------------------------------------------
-----------A------------------------------------------------
-----------------DS-ASTQKAEREVTKMVVVMVLGFLVCWAPYASFSLWIVSHRG
EE--FDLR-MATIPSCLSKASTVYNPVIYVLMNKQFRSCMMKMV-----C-GKNIE-EDE
-AS-TS-SQVTQVS----------------------------------------------
------------------------------------------------------------
-SVAPEK
>M13299    1 human BCP <>[Science232(4747),193-202'86]
MRKMSEE---------------------------EFYL--------F-------------
-----------KN-IS-------------------S--VGPWDGPQYH-IAPVWAFYLQA
AFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIF-SVFPVF-VASC
N-GYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-FRFSSKHALTVV
LATWTIGIGV-SIPPF-FGWSR-----FIPEGLQ---CSCGPDWYTVGTKYRSESYTWFL
FIFCFIVPLSLICFSYTQLLRALKAVAAQQ------------------------------
------------------------------------------------------------
-----------Q------------------------------------------------
-----------------ES-ATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRN
HG--LDLR-LVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMV-----C-GKAMTDESD
T---CS-SQKTEVS-------------T--------------------------------
----------------------------------------------------------VS
STQVGPN
>K03494    1 human GCP <>[Science232(4747),193-202'86]
MAQQWSLQ-RLAGRH---PQD--S--YEDSTQSSIFTYT-------N-------------
-----------SN---------------------ST--RGPFEGPNYH-IAPRWVYHLTS
VWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVI-ASTISV-VNQV
Y-GYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-VRFDAKLAIVGI
AFSWIWAAVW-TAPPI-FGWSR-----YWPHGLK---TSCGPDVFSGSSYPGVQSYMIVL
MVTCCITPLSIIVLCYLQVWLAIRAVAKQQ------------------------------
------------------------------------------------------------
-----------K------------------------------------------------
-----------------ES-ESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPG
YP--FHPL-MAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFG------KKVDDGS-E
LSSASK----TEVS-------------S--------------------------------
------------------------------------------------------------
VSSVSPA
>Z68193    1 human Red Opsin <>[]
MAQQWSLQ-RLAGRH---PQD--S--YEDSTQSSIFTYT-------N-------------
-----------SN---------------------ST--RGPFEGPNYH-IAPRWVYHLTS
VWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVI-ASTISI-VNQV
S-GYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGI
AFSWIWSAVW-TAPPI-FGWSR-----YWPHGLK---TSCGPDVFSGSSYPGVQSYMIVL
MVTCCIIPLAIIMLCYLQVWLAIRAVAKQQ------------------------------
------------------------------------------------------------
-----------K------------------------------------------------
-----------------ES-ESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPG
YA--FHPL-MAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFG------KKVDDGS-E
LSSASK----TEVS-------------S--------------------------------
------------------------------------------------------------
VSSVSPA
>M92036    1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
MTEAWNVA-VFAARR---SR---D--DDDTTRGSVFTYT-------N-------------
-----------TN---------------------NT--RGPFEGPNYH-IAPRWVYNLVS
FFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLV-ASTISV-FNQI
F-GYFILGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-IKFDSKLAIIGI
VFSWVWAWGW-SAPPI-FGWSR-----YWPHGLK---TSCGPDVFSGSVELGCQSFMLTL
MITCCFLPLFIIIVCYLQVWMAIRAVAAQQ------------------------------
------------------------------------------------------------
-----------K------------------------------------------------
-----------------ES-ESTQKAEREVSRMVVVMIVAFCICWGPYASFVSFAAANPG
YA--FHPL-AAALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLFG------KKVDDGS-E
ASTTSR----TEVS-------------S--------------------------------
----------------------------------------------------------VS
NSSVAPA
>M62903    1 chicken visual pigment <>[BBRC173,1212-1217'90]
MAAWEAAF-AA--RR----RH--E--EEDTTRDSVFTYT-------N-------------
-----------SN---------------------NT--RGPFEGPNYH-IAPRWVYNLTS
VWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVI-ASTISV-INQI
S-GYFILGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-IKFDGKLAVAGI
LFSWLWSCAW-TAPPI-FGWSR-----YWPHGLK---TSCGPDVFSGSSDPGVQSYMVVL
MVTCCFFPLAIIILCYLQVWLAIRAVAAQQ------------------------------
------------------------------------------------------------
-----------K------------------------------------------------
-----------------ES-ESTQKAEKEVSRMVVVMIVAYCFCWGPYTFFACFAAANPG
YA--FHPL-AAALPAYFAKSATIYNPIIYVFMNRQFRNCILQLFG------KKVDDGS-E
V-STSR----TEVS-------------S--------------------------------
----------------------------------------------------------VS
NSSVSPA
>S75720    1 chicken P-opsin <>[Science267(5203),1502-1506'95]
MSSNSSQA--------------------------------------P-------------
-----------PN---------------------GT--PGPFDGPQWPYQAPQSTYVGVA
VLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLC-GSSVSL-SNNI
N-GFFVFGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-FQFQRRHAVSGC
AFTWGWALLW-SAPPL-LGWSS-----YVPEGLR---TSCGPNWYTGG--SNNNSYILSL
FVTCFVLPLSLILFSYTNLLLTLRAAAAQQ------------------------------
------------------------------------------------------------
-----------K------------------------------------------------
-----------------EA-DTTQRAEREVTRMVIVMVMAFLLCWLPYSTFALVVATHKG
II--IQPV-LASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLC----C-GYQPQRT-G
KASPGTPGPHADVT---------AAGLR--------------------------------
----------------------------------------------------------NK
VMPAHPV
>M17718    1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
MESGNVSS-SL-FGN-VSTA-----------LRPEA-RL-------S-------------
--------A--E--TR---------LLGWNVPPEELRHIPEH-WLTYP-EPPESMNYLLG
TLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMM-V-KTPIFI-YNSF
H-QGYALGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMI
IFIYMYATPW-VVACYTETWGR-----FVPEGYL---TSCTFDYLTDN--FDTRLFVACI
FFFSFVCPTTMITYYYSQIVGHVFSHEKAL------------------------------
------------------------------------------------------------
-----------RDQ------A---------------------K-----------------
-----KMNVESL---RSNVDKNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAFGDK
TL--LTPG-ATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLA--LNEK-AP-ES
-SAVAS-TSTT----------------Q--------------------------------
-----------------------------------------------------------E
PQQTTAA
>X65879    1 Drosophila pseudoobscura Rh3 <>[Genetics132(1),193-204'92
MEYHNVSS--V-LGN-VSSV-----------LRPDA-RL-------S-------------
--------A--E--SR---------LLGWNVPPDELRHIPEH-WLIYP-EPPESMNYLLG
TLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMM-I-KTPIFI-YNSF
H-QGYALGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMI
IFIYLYATPW-VVACYTESWGR-----FVPEGYL---TSCTFDYLTDN--FDTRLFVACI
FFFSFVCPTTMITYYYSQIVGHVFSHEKAL------------------------------
------------------------------------------------------------
-----------RDQ------A---------------------K-----------------
-----KMNVDSL---RSNVDKSKEAAEIRIAKAAITICFLFFASWTPYGVMSLIGAFGDK
TL--LTPG-ATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLA--ISEK-AP-ES
-RAAIS-TSTT----------------Q--------------------------------
-----------------------------------------------------------E
QQQTTAA
>M17730    1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
MEPLCNAS-EP--------P-----------LRPEA-RS---------------------
--------S-GNGDLQ---------FLGWNVPPDQIQYIPEH-WLTQL-EPPASMHYMLG
VFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMC-L-KAPIFN-SFHR
G-FAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMN
IIIWLYCTPW-VVLPLTQFWDR-----FVPEGYL---TSCSFDYLSDN--FDTRLFVGTI
FFFSFVCPTLMILYYYSQIVGHVFSHEKAL------------------------------
------------------------------------------------------------
-----------REQ------A---------------------K-----------------
-----KMNVESL---RSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDK
SL--LTQG-ATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLG--VNEK-SG-EI
-SSAQS-TT-T----------------Q--------------------------------
-----------------------------------------------------------E
QQQTTAA
>X65880    1 Drosophila pseudoobscura Rh4 <>[Genetics132(1),193-204'92
MDALCNAS-EP--------P-----------LRPEA-RM-------S-------------
--------S-GSDELQ---------FLGWNVPPDQIQYIPEH-WLTQL-EPPASMHYMLG
VFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMC-L-KAPIFI-YNSF
H-RGFALGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMN
IIIWLYCTPW-VVLPLTQFWDR-----FVPEGYL---TSCSFDYLSDN--FDTRLFVGTI
FLFSFVVPTLMILYYYSQIVGHVFNHEKAL------------------------------
------------------------------------------------------------
-----------REQ------A---------------------K-----------------
-----KMNVESL---RSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDK
SL--LTPG-ATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLG--VNEK-SG-EA
-SSAQS-TTTQ----------------E--------------------------------
-----------------------------------------------------------Q
TQQTSAA
>D50584    1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
MTNATGPQ-MAYYGA-ASMD-----------FG-----Y-------P-------------
--------E-G---VS----------IVDFVRPEIKPYVHQH-WYNYP-PVNPMWHYLLG
VIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTT-NVPFFT-YNCF
SGGVWMFSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-PKLTTGKAVVFA
LISWVIAIGC-ALPPF-FGWGN-----YILEGIL---DSCSYDYLTQD--FNTFSYNIFI
FVFDYFLPAAIIVFSYVFIVKAIFAHEAAM------------------------------
------------------------------------------------------------
-----------RAQ------A---------------------K-----------------
-----KMNVSTL---RSNE-ADAQRAEIRIAKTALVNVSLWFICWTPYALISLKGVMGDT
SG--ITPL-VSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFC--VHET-ET-KS
-NDDSQ-SNS--------------------------------------------------
------------------------------------------------------------
TVAQDKA
>D50583    1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
MANVTGPQ-MAFYGS-GAAT-----------FG-----Y-------P-------------
--------E-G---MT----------VADFVPDRVKHMVLDH-WYNYP-PVNPMWHYLLG
VVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTT-NFPPFC-YNCF
SGGRWMFSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-PKLTQGKATFMC
GLAWVISVGW-SLPPF-FGWGS-----YTLEGIL---DSCSYDYFTRD--MNTITYNICI
FIFDFFLPASVIVFSYVFIVKAIFAHEAAM------------------------------
------------------------------------------------------------
-----------RAQ------A---------------------K-----------------
-----KMNVTNL---RSNE-AETQRAEIRIAKTALVNVSLWFICWTPYAAITIQGLLGNA
EG--ITPL-LTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFC--VHEK-DP-ND
-VEENQ-SSN--------------------------------------------------
------------------------------------------------------------
TQTQEKS
>K02320    1 D.melanogaster opsin <>[Cell40,851-858'85]
MESFAVAA----------AQ-----------LGPHF-AP-------L-------------
-----------SN-GS----------VVDKVTPDMAHLISPY-WNQFP-AMDPIWAKILT
AYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMIT-NTPMMG-INLY
F-ETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLAL---
-------------------GKM-----YVPEGNL---TSCGIDYLERD--WNPRSYLIFY
SIFVYYIPLFLICYSYWFIIAAVSAHEKAM------------------------------
------------------------------------------------------------
-----------REQ------A---------------------K-----------------
-----KMNVKSL---RSSED-AEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFK-F
EG--LTPL-NTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV--FGKVDDGK-S
-SD-AQ-SQAT-------------------------------------------------
-----------------------------------------------------------A
SEAESKA
>K02315    1 D.melanogaster ninaE <>[Cell40,839-850'85]
MESFAVAA----------AQ-----------LGPHF-AP-------L-------------
-----------SN-GS----------VVDKVTPDMAHLISPY-WNQFP-AMDPIWAKILT
AYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMIT-NTPMMG-INLY
F-ETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKI
AYIWFMSSIW-CLAPA-FGWSR-----YVPEGNL---TSCGIDYLERD--WNPRSYLIFY
SIFVYYIPLFLICYSYWFIIAAVSAHEKAM------------------------------
------------------------------------------------------------
-----------REQ------A---------------------K-----------------
-----KMNVKSL---RSSED-AEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFK-F
EG--LTPL-NTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV--FGKVDDGK-S
-SD-AQ-SQAT-------------------------------------------------
-----------------------------------------------------------A
SEAESKA
>X65877    1 Drosophila pseudoobscura ninaE <>[Genetics132(1),193-204'
MDSFAAVA----------TQ-----------LGPQF-AA-------P-------------
-----------SN-GS----------VVDKVTPDMAHLISPY-WDQFP-AMDPIWAKILT
AYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMIT-NTPMMG-INLY
F-ETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKI
AYIWFMSTIWCCLAPV-FGWSR-----YVPEGNL---TSCGIDYLERD--WNPRSYLIFY
SIFVYYIPLFLICYSYWFIIAAVSAHEKAM------------------------------
------------------------------------------------------------
-----------REQ------A---------------------K-----------------
-----KMNVKSL---RSSED-ADKSAEGKLAKVALVTISLWFMAWTPYLVINCMGLFK-F
EG--LTPL-NTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV--FGKVDDGK-S
-SE-AQ-SQAT-------------------------------------------------
-----------------------------------------------------------T
SEAESKA
>M12896    1 D.melanogaster Rh2 <>[Cell44,705-710'86]
MERSHLPE-TPFDL----AH-----------SGPRF-QA-------Q-------------
--------S-SGN-GS----------VLDNVLPDMAHLVNPY-WSRFA-PMDPMMSKILG
LFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMAS-QSPVMI-INFY
Y-ETWVLGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKI
LFIWMMAVFW-TVMPL-IGWSA-----YVPEGNL---TACSIDYMTRM--WNPRSYLITY
SLFVYYTPLFLICYSYWFIIAAVAAHEKAM------------------------------
------------------------------------------------------------
-----------REQ------A---------------------K-----------------
-----KMNVKSL---RSSED-CDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLFK-I
DG--LTPL-TTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCV--FGNTDEPK-P
-DAPAS-DTET-------------------------------------------------
-----------------------------------------------------------T
SEADSKA
>X65878    1 Drosophila pseudoobscura Rh2 <>[Genetics132(1),193-204'92
MERSLLPE-PPLAM----AL-----------LGPRF-EA-------Q-------------
--------T-GGN-RS----------VLDNVLPDMAPLVNPH-WSRFA-PMDPTMSKILG
LFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMAS-QSPVMI-INFY
Y-ETWVLGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKI
AFIWMMAVFW-TIMPL-IGWSS-----YVPEGNL---TACSIDYMTRQ--WNPRSYLITY
SLFVYYTPLFMICYSYWFIIATVAAHEKAM------------------------------
------------------------------------------------------------
-----------RDQ------A---------------------K-----------------
-----KMNVKSL---RSSED-CDKSAENKLAKVALTTISLWFMAWTPYLIICYFGLFK-I
DG--LTPL-TTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCV--CGTTDEPK-P
-DAPPS-DTET-------------------------------------------------
-----------------------------------------------------------T
SEAESKD
>U26026    1 Apis mellifera long-wavelength rhodopsin <>[]
MIAVSGPS-YE-A-----FS-----------YGGQ--AR-------F-------------
-----------NN-QT----------VVDKVPPDMLHLIDAN-WYQYP-PLNPMWHGILG
FVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFC-MSPPMV-INCY
Y-ETWVLGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-KPLSINGALIRI
IAIWLFSLGW-TIAPM-FGWNR-----YVPEGNM---TACGTDYFNRG--LLSASYLVCY
GIWVYFVPLFLIIYSYWFIIQAVAAHEKNM------------------------------
------------------------------------------------------------
-----------REQ------A---------------------K-----------------
-----KMNVASL---RSSEN-QNTSAECKLAKVALMTISLWFMAWTPYLVINFSGIFN-L
VK--ISPL-FTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLA--CAAEPSS-DA
-VSTTS-GTTT----------------V--------------------------------
-----------------------------------------------------------T
DNEKSNA
>L03781    1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
MANQLSYS-SL-G-----WP-----------YQ---------------------------
-----------PN-AS----------VVDTMPKEMLYMIHEH-WYAFP-PMNPLWYSILG
VAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAF-MMPTMT-SNCF
A-ETWILGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-APLTHKKATLLL
LFVWIWSGGW-TILPF-FGWSR-----YVPEGNL---TSCTVDYLTKD--WSSASYVVIY
GLAVYFLPLITMIYCYFFIVHAVAEHEKQL------------------------------
------------------------------------------------------------
-----------REQ------A---------------------K-----------------
-----KMNVASL---RANADQQKQSAECRLAKVAMMTVGLWFMAWTPYLIISWAGVFSSG
TR--LTPL-ATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLA--CGSGESGSDV
-KSEAS-ATTT----------------M--------------------------------
----------------------------------------------------------EE
KPKIPEA
>X07797    1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
MVESTTLV-NQ-T-----------------------------------------------
----------------------------WWYNP--TVDIHPH-WAKFD-PIPDAVYYSVG
IFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKT-ISAF
M-KKWIFGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMI
IFVWMWSIVW-SVGPV-FNWGA-----YVPEGIL---TSCSFDYLSTD--PSTRSFILCM
YFCGFMLPIIIIAFCYFNIVMSVSNHEKEM------------------------------
------------------------------------------------------------
-----------AAM------A---------------------K-----------------
-----RLNAKEL---RKA--QAGASAEMKLAKISMVIITQFMLSWSPYAIIALLAQFGPA
EW--VTPY-AAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKECED
-ANDAE-EEVV---------------ASERGGE--SRDAAQMKEMMAMMQKMQAQQAAYQ
PPPPPQGYPPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGV
DNQAYQA
>X70498    1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
MGRDLR-D-NE-T-----------------------------------------------
----------------------------WWYNP--SIVVHPH-WREFD-QVPDAVYYSLG
IFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMT-ISCF
L-KKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMI
IFVWLWSVLW-AIGPI-FGWGA-----YTLEGVL---CNCSFDYISRD--STTRSNILCM
FILGFFGPILIIFFCYFNIVMSVSNHEKEM------------------------------
------------------------------------------------------------
-----------AAM------A---------------------K-----------------
-----RLNAKEL---RKA--QAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPL
EW--VTPY-AAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETED
-DKDAE-TEIP---------------AGESSDAAPSADAAQMKEMMAMMQKMQQQQAAYP
PQG----YAPPPQGYPPQGYPPQGYPPQGYPPQGY---PPPPQGAPPQG-APPAAPPQGV
DNQAYQA
>L21195    1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
MMDVNSSGRPDLY-G----HLRS-FLLPEVGRGLPDLSPDGG----A---D---------
------PVAGSWA-PHLLSEVTASPAPTWDAPPDNA--SGCGEQINYG----RVEKVVIG
SILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVA-VMPFVSVTDLI
G-GKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMI
LSVWLLSASI-TLPPL-FGWAQ-----NVNDDKV---CLISQD----------FGYTIYS
TAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFP------------------------
----------------------------RVE--------------PDSVI----------
-ALNG-IVKLQKEV------E---------------------E-----------------
-----CANLSRLLKHERKN-ISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICG
TSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQ----C-QYRNINRK-
LSAAGMH-EALKLAERPERPEFVLQNAD--------------------------------
----------------------------------------------------------YC
RKKGHDS
>L15228    1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
MPHLLSG-FLE-------------------------------------------------
--------------------VTASPAPTWDAPPDNV--SGCGEQINYG----RVEKVVIG
SILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVA-VMPFVSVTDLI
G-GKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMI
LSVWLLSASI-TLPPL-FGWAQ-----NVNDDKV---CLISQD----------FGYTIYS
TAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFP------------------------
----------------------------RVQ--------------PESVI----------
-SLNG-VVKLQKEV------E---------------------E-----------------
-----CANLSRLLKHERKN-ISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICG
TSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQ----C-QYRNINRK-
LSAAGMH-EALKLAERPERSEFVLQNSD--------------------------------
----------------------------------------------------------HC
GKKGHDT
>A47425  serotonin receptor 5HT-7 - rat
MPHLLSG-FLE-------------------------------------------------
--------------------VTASPAPTWDAPPDNV--SGCGEQINYG----RVEKVVIG
SILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVA-VMPFVSVTDLI
G-GKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMI
LSVWLLSASI-TLPPL-FGWAQ-----NVNDDKV---CLISQD----------FGYTIYS
TAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFP------------------------
----------------------------RVQ--------------PESVI----------
-SLNG-VVKLQKEV------E---------------------E-----------------
-----CANLSRLLKHERKN-ISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICG
TSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQ----C-QYRNINRK-
LSAAGMH-EALKLAERPERSEFVLQNSD--------------------------------
----------------------------------------------------------HC
GKKGHDT
>M83181    1 human serotonin receptor <>[JBC267(11),7553-7562'92]
MDVLSPG-QGNNTTS---PP-----------------AP-------F-------------
-------ET-GGN-TTG-------------IS-------------DVT----VSYQVITS
LLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVL-VLPMAA-LYQV
L-NKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALI
SLTWLIGFLI-SIPPM-LGWRT-----PEDRSDPD-ACTISKD----------HGYTIYS
TFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT-------------------
--------------------RHGASPAPQPKKSVNGESGSRNWRL--GVESKAGGALCAN
GAVRQGDDGAA------------------------LEVIEVHRVGNSKEHLPLPSEAGPT
PCAPASFERKNERNAEAKR-KMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCES
SC-HMPTL-LGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK----C-K--------
------------------------------------------------------------
------------------------------------------------------------
---FCRQ
>A35181  serotonin receptor class 1A - rat
MDVFSFG-QGNNTTA---SQ-----------------EP-------F-------------
-------GT-GGN-VTS-------------IS-------------DVT----FSYQVITS
LLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVL-VLPMAA-LYQV
L-NKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALI
SLTWLIGFLI-SIPPM-LGWRT-----PEDRSDPD-ACTISKD----------HGYTIYS
TFGAFYIPLLLMLVLYGRIFRAARFRIRKTVRKVEKKGAGT-------------------
--------------------SLGTSSAPPPKKSLNGQPGSGDWRR--CAENRAVGTPCTN
GAVRQGDDEAT------------------------LEVIEVHRVGNSKEHLPLPSESGSN
SYAPACLERKNERNAEAKR-KMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCES
SC-HMPAL-LGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK----C-K--------
------------------------------------------------------------
------------------------------------------------------------
---FCRR
>L06803    1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFG-DLALDVARMGGLASTPSGLRSTGLTTPGLSPTGLVTSDFNDSYGLTGQFING
SHSSRSRDNASAN-DTSATNM--TDDRYWSLT-------------VYS----HEHLVLTS
VILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVL-VMPLSV-VSEI
S-KVWFLHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTSIDYI-RRRSARRILLMI
MVVWIVALFI-SIPPL-FGWRD-----PNNDPDKTGTCIISQD----------KGYTIFS
TVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDC
NGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKN-RAKK------LPENAN----------
-GVNS-NSSSS-ERLKQIQIETAEAFANGCAEEASIAML-ERQCNNGKKIS---------
--------SNDTPYSRTRE-KLELKRERKAARTLAIITGAFLICWLPFFIIALIGPFVDP
EG--IPPF-ARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILF----G-K-Y------
------------------------------------------------------------
------------------------------------------------------------
--RRGHR
>A47174  serotonin receptor, 5HTlym receptor - great pond snail
MANFTFG-DLALDVARMGGLASTPSGLRSTGLTTPGLSPTGLVTSDFNDSYGLTGQFING
SHSSRSRDNASAN-DTSATNM--TDDRYWSLT-------------VYS----HEHLVLTS
VILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVL-VMPLSV-VSEI
S-KVWFLHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTSIDYI-RRRSARRILLMI
MVVWIVALFI-SIPPL-FGWRD-----PNNDPDKTGTCIISQD----------KGYTIFS
TVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDC
NGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKN-RAKK------LPENAN----------
-GVNS-NSSSS-ERLKQIQIETAEAFANGCAEEASIAML-ERQCNNGKKIS---------
--------SNDTPYSRTRE-KLELKRERKAARTLAIITGAFLICWLPFFIIALIGPFVDP
EG--IPPF-ARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILF----G-K-Y------
------------------------------------------------------------
------------------------------------------------------------
--RRGHR
>X95604    1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
MEGAEGQ-EE-LDWEALYLRL--P--LQNCSWNSTGWEP---------------------
----------NWN-VTVV-----PNTTWWQAS-------APFDT-PAA----LVRAAAKA
VVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACL-VMPLGA-VYEV
V-QRWTLGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTNIDYI-HASTAKRVGMMI
ACVWTVSFFV-CIAQL-LGWKDPDWNQRVSEDLR---CVVSQD----------VGYQIFA
TASSFYVPVLIILILYWRIYQTARKRIRRRRGATARGGVGPP-------------PVPAG
GALVAGGGSGGIAAAVVAVIGRPLPTISETTTT-GF--------T--NVS----------
-SNNT-SP----EK------Q---------------------SCANGLEADPPTTGYG--
--AVAAAYYPSLVRRKPKE-AADSKRERKAAKTLAIITGAFVACWLPFFVLAILVPTCD-
CE--VSPV-LTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLC----G-R-RV-----
------------------------------------------------------------
------------------------------------------------------------
RRRRAPQ
