LOCUS       MUSCRKNB                4521 bp    DNA     linear   ROD 24-JUN-1993
DEFINITION  Mouse creatine kinase B gene, complete cds.
ACCESSION   M74149
VERSION     M74149.1  GI:192727
KEYWORDS    creatine kinase B.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus.
REFERENCE   1  (bases 1 to 4521)
  AUTHORS   van Deursen,J., Schepens,J., Peters,W., Meijer,D., Grosveld,G.,
            Hendriks,W. and Wieringa,B.
  TITLE     Genetic variability of the murine creatine kinase B gene locus and
            related pseudogenes in different inbred strains of mice
  JOURNAL   Genomics 12 (2), 340-349 (1992)
  MEDLINE   92155725
PUBMED   1740343
COMMENT     Original source text: Mus musculus Liver DNA.
FEATURES             Location/Qualifiers
     source          1..4521
                     /organism="Mus musculus"
                     /db_xref="taxon:10090"
                     /tissue_type="Liver"
     repeat_region 140..155
     CAAT_signal 1287..1290
     TATA_signal 1304..1307
     CAAT_signal 1317..1320
     TATA_signal 1341..1344
     mRNA join(1363..1439,1696..1903,2090..2244,2322..2454,
                     2624..2795,3381..3504,3652..3841,3925..4301)
                     /product="creatine kinase"
     prim_transcript 1363..4301
                     /note="putative"
                     /function="primary transcript of murine creatine kinase B
                     gene"
     exon 1363..1439
     exon 1696..1903
     CDS join(1711..1903,2090..2244,2322..2454,2624..2795,
                     3381..3504,3652..3841,3925..4103)
                     /codon_start=1
                     /product="creatine kinase"
                     /protein_id="AAA37462.1"
                     /db_xref="GI:192728"
                     /translation="MPFSNSHNTQKLRFPAEDEFPDLSSHNNHMAKVLTPELYAELRA
                     KCTPSGFTLDDAIQTGVDNPGHPYIMTVGAVAGDEESYDVFKDLFDPIIEERHGGYQP
                     SDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVE
                     ALSSLDGDLSGRYYALKSMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIW
                     HNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPH
                     LGYILTCPSNLGTGLRAGVHIKLPHLGKHEKFSEVLKRLRLQKRGTGGVDTAAVGGVF
                     DVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQAIDDLMPAQK"
     exon 2090..2244
     exon 2322..2454
     exon 2624..2795
     exon 3381..3504
     exon 3652..3841
     exon 3925..4301
     3'UTR 4104..4301
     polyA_signal 4279..4284
     repeat_region 4338..4365
BASE COUNT      875 a   1334 c   1334 g    978 t
ORIGIN      
        1 ctgcagctgg acgtggtggc ccatgccttt aatcccagca cttcggaggc agaggcaggc
       61 gaatttctga gttcgaggcc agcctggtct acagagtgag ttccaggaca gccagggcta
      121 tacagagaaa ccctgtctta aacaaacaaa caaaccaaaa aagaaaaaaa gaaagggtgt
      181 gccgccacgc aggacctcac ctctctattt gtatcaactg caccatctac cacacttttc
      241 tacccacgac cattccctaa tgagcatcag atcgaatcca aactttctcc ctctacacgt
      301 ttcctgatct gtttgtagag aagggacacc gtctttctgt aggctgcatt ccatgaagtg
      361 ggaatgctag gtcatagagc aatttaaaaa ttttttaaca aatactgcca aattactttc
      421 cagaaaaaga tgaagctgct ggcagctgca gcaggcaagg tgcgaacgcc tatcttcaca
      481 cattccaatt cacacctggc actggctgtg gtcaaattcc aggtttcccc tgtgtgtgtg
      541 tgtggggggg ggggtggcac ggggagagag actgtttcaa tgtgttggat ctgattaatg
      601 agcttaattt tgactggtgc ttcctccacc cccagtttgc ctgccggtgt tggggagttc
      661 tttgtgggtg cggtggtaga aaccggtccc ccgagaaaag ggacaggaga tgagaatttg
      721 gagattcaaa aacagtctct aggaactaaa tgtcttgaat ctttcagggt ctgggtccaa
      781 gggtcttggc ggtgttcctt agagcccgcc caaggtcaga acaccctggg tgcttccggg
      841 caggacctca gccagactgc gcctctggtg ttgcaccaag aacacccagg agatgcccgc
      901 aggcaccttg aggaaggtcg gcggctctgt ggctcttgag gatatggcct ggatgcggtg
      961 tttggatgct gtacccaatg ttaaaaacct ggactctcac catgaccctc tctacaacgc
     1021 agtcggcctg aggagacagg gaaggcagga gcctcaagtg ccatctggct tcccagactc
     1081 agtttcctgc ccccaggcag tgtgtgtgaa gcaggtctag gatatctatg gctctggggt
     1141 ttcgtcttag ggatcctgtg cgagcaccac cggggtggcc aaactgcgca gcggggtcga
     1201 gacttgggga ccgctagggt gggccgctgg gggtgtcaag ggctgctgcc tcggacaaag
     1261 cggcggcacc accccaaagc gcggaccaat ggaatgaatg ggctataaat agccgccaat
     1321 gggaggccgc gacgcgcccc ttaagagctc agggagcagc gagcagccgt cgttcttctg
     1381 cgctgcgcca ggagctgcaa gcacaggcat ccatcgcccc tgcttcgtcc ggcatcccgg
     1441 tgagcgggtc caagggccag gggtatagtc ctgcggggct ctacgctgtg gggtgcggga
     1501 ccggggcatc acgccgagcc tcgctgccgg gagcgctcat cggacccgcc cgggaacttg
     1561 ggatgcgctg gactctgacg atgcagacct cgctgacctt ggtggcgtcc agggaaagtc
     1621 tcgggggtcc caagtggttt gcaggtccct ggcggccggt gtttaaatct cctctgaccc
     1681 cgctcttccc tgcagcccgc tgccgccgcc atgcccttct ccaacagcca taatacgcag
     1741 aagctgcgct tcccggccga ggatgagttc cctgatctga gcagccacaa caaccatatg
     1801 gccaaggtgc tgaccccgga gctgtacgcc gagctccgtg ccaagtgcac gccgagcggc
     1861 tttactttgg acgacgccat tcagactggc gtagacaatc cgggtatgca cacccctgta
     1921 gcgtcaggct tccgcctccc caagaagccc cccgggcaag gatcccactg ctcttccctg
     1981 aaccttcggt gggctggggt cccctgttcc cctctccgcg cttagcctta agagcctcgg
     2041 cttgctcctg cctgacggtg acgtcactgt cgccgcgccc ctcctccagg ccacccgtac
     2101 atcatgactg tgggtgcagt ggcgggcgac gaggagagtt acgacgtatt caaggacctc
     2161 ttcgacccca ttattgagga gcggcacggc ggctaccagc ccagtgatga gcacaagacc
     2221 gacctcaacc cagacaacct gcaggtgcgg ggaatcaggg tccgggcgtg ctggggagag
     2281 gggtctcggc gctcactctg gccaccacct tgtattccca gggtggcgat gacctggacc
     2341 ccaactacgt gctgagctcg cgagtgcgca caggccgcag catccgcggc ttctgtctcc
     2401 ccccgcactg cagccgcggg gagcgccgcg ccatcgagaa gctggcagta gaaggtaggg
     2461 gtcgggtaac agccgccaga gctgctgcgc tcttctctgc gcgcgcgttc ccactgggga
     2521 ctgaggtcga agacccacct tcgcccgcgg ggacacactg ctgcaggcgg ggcggcgggc
     2581 ttgctcgccc gcccaccctg tccttgaact ctgcactccg cagctctgtc cagcctagat
     2641 ggcgacctgt ctggcaggta ctacgcgctc aagagcatga ctgaggcgga gcagcagcag
     2701 ctcattgacg accacttcct cttcgataag cctgtgtcgc ctctgctgct ggcctccggc
     2761 atggcccgcg actggccgga tgctcgtggc atatggtacg agccctctcc ccccccagtc
     2821 cccagaaggt ggggcctgcc ctgaattcct agtttgtgca gtgcctccct ccgcccaggt
     2881 gaccttggtt ctgccgatga ctgtggtcct tgcgctgcgg gaggccgcag tctccaggga
     2941 ctcaagggtg gtgaccagtc tctttggcgt ctgttctccg ccctcctcct gggagccggc
     3001 gcttcttgtt ttctctccac cttctcaccc ccttattccg ccgggatcgt gccaggtgcc
     3061 aatgacgcaa aagcctccgc accgtccggg cagggctcct acccctgcag actgagcggg
     3121 cggaggcgtg cttcctctag tgggatgctc tggaggctcc agacccttgc gggccacaca
     3181 gcacatgact ggtgattgag atgtatatga gctgccttcc tccactgttg ctgggattgg
     3241 cgtcttggtg acagctcaca ttccagcact ttgttgagga agcattttgt ttgaggtcac
     3301 ccacctatag tgtctttctt gggtgtgatc taaggccaca ttctggcagg gactccagcc
     3361 tgactttacc cctcttctag gcacaatgac aataagactt tcctggtgtg gattaacgag
     3421 gaggaccacc tgcgagtcat ctccatgcag aaggggggca acatgaagga agtgttcacc
     3481 cgattctgca ccggcctcac tcaggtcagg cctgggcatt ccccagggct tcctcactag
     3541 gggcgttggt gctggggagg gatcaggggc agatcagagc ccacatctcc cagggtccgt
     3601 agggcttccg gccaggcttc cttctcttaa ctctcccttc tccaccttca gatcgaaact
     3661 ctcttcaagt ccaagaacta tgagttcatg tggaatcctc acctgggcta catcctcaca
     3721 tgcccatcca acctgggcac cggactgcgg gcaggtgtac acatcaagct gccccacctg
     3781 gggaagcacg agaagttctc ggaggtgctc aagcggctgc ggcttcagaa gcgaggcaca
     3841 ggtgaggggc agaaggcaca ggtgaggggc agaaggtgca ggtgttgtcc tcagccccgc
     3901 tgacctgccc atgtcccacc gcaggtggcg tggacaccgc tgctgtcggt ggggtgtttg
     3961 atgtctccaa cgctgaccgc ctgggcttct cggaggtgga actggtgcag atggtggtgg
     4021 acggagtgaa actactcatt gagatggagc aacggctcga gcagggtcag gcaatcgatg
     4081 acctcatgcc ggcccagaag tgaagcctgg ccctcgccac catcaggctg ccgcttccta
     4141 acttattacc cgggcagtgc ccgccatgca tccttgatgt ttgccgcctg gcgctgagcc
     4201 cttagcctcg ctgtagagac ttctgtcgcc ctgggtagag tttatttttt tgatggctaa
     4261 gctgttgctg acactgaaaa taaactaggg tttggcctgc cctatgtccg agtgttgctt
     4321 ctcctttcct agagacagtg tgtgtgtgtg tgtgtgtatg tgtgtgcgcg agctggcctt
     4381 ctgtgtcatc tcacctagca gatgaaacat gagccataga agatacaggg cagagaggga
     4441 gggaggctct gagtccagcc ttgagcatct aaggacatct gtgcttgcag ggtggagcct
     4501 tagtgtttcc ttagtcccag c
//
